Association between statin use and outcomes in patients with coronavirus disease 2019 (COVID-19): a nationwide cohort study

JH Butt, TA Gerds, M Schou, K Kragholm, M Phelps… - BMJ open, 2020 - bmjopen.bmj.com
Objective To investigate the association between recent statin exposure and risk of severe
COVID-19 infection and all-cause mortality in patients with COVID-19 in Denmark. Design …

[HTML][HTML] Statins use and COVID-19 outcomes in hospitalized patients

SK Ayeh, EJ Abbey, BAA Khalifa, RD Nudotor… - PLoS …, 2021 - journals.plos.org
Background There is an urgent need for novel therapeutic strategies for reversing COVID-19-
related lung inflammation. Recent evidence has demonstrated that the cholesterol-lowering …

[HTML][HTML] Statin use is associated with lower disease severity in COVID-19 infection

WYT Tan, BE Young, DC Lye, DEK Chew, R Dalan - Scientific reports, 2020 - nature.com
We aim to study the association of hyperlipidemia and statin use with COVID-19 severity. We
analysed a retrospective cohort of 717 patients admitted to a tertiary centre in Singapore for …

[HTML][HTML] Protective effects of statins on COVID-19 risk, severity and fatal outcome: a nationwide Swedish cohort study

A Santosa, S Franzén, J Nåtman, B Wettermark… - Scientific Reports, 2022 - nature.com
The impact of statins on COVID-19 remains unclear. This study aims to investigate whether
statin exposure assessed both in the population and in well-defined cohorts of COVID-19 …

Statin use and clinical outcomes in patients with COVID-19: An updated systematic review and meta-analysis

R Pal, M Banerjee, U Yadav… - Postgraduate medical …, 2022 - academic.oup.com
Purpose Observations studies have shown that prior use of statins is associated with a
reduced risk of adverse clinical outcomes in patients with COVID-19. However, the available …

[HTML][HTML] Statins in patients with COVID-19: a retrospective cohort study in Iranian COVID-19 patients

P Peymani, T Dehesh, F Aligolighasemabadi… - Translational medicine …, 2021 - Springer
Background The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has profoundly affected the …

[HTML][HTML] The association between the use of statins and clinical outcomes in patients with COVID-19: a systematic review and meta-analysis

CS Kow, SS Hasan - American Journal of Cardiovascular Drugs, 2022 - Springer
Purpose Previously, we have reported potential clinical benefits with the use of statins in
patients with coronavirus disease 2019 (COVID-19) in a meta-analysis, where there was a …

[HTML][HTML] The effect of statins on clinical outcome among hospitalized patients with COVID-19: a multi-centric cohort study

S Umakanthan, S Senthil, S John… - Frontiers in …, 2022 - frontiersin.org
The coronavirus disease-2019 (COVID-19) is caused by SARS-CoV-2, leading to acute
respiratory distress syndrome (ARDS), thrombotic complications, and myocardial injury …

[HTML][HTML] The protective association between statins use and adverse outcomes among COVID-19 patients: a systematic review and meta-analysis

R Chow, J Im, N Chiu, L Chiu, R Aggarwal, J Lee… - PLoS …, 2021 - journals.plos.org
Introduction Statins may reduce a cytokine storm, which has been hypothesized as a
possible mechanism of severe COVID-19 pneumonia. The aim of this study was to conduct a …

Statin use and mortality in COVID-19 patients: Updated systematic review and meta-analysis

A Kollias, KG Kyriakoulis, IG Kyriakoulis, T Nitsotolis… - Atherosclerosis, 2021 - Elsevier
Background and aims Statin therapy is administered to patients with high cardiovascular
risk. These patients are also at risk for severe course of coronavirus disease 2019 (COVID …