Low levels of antibodies against phosphorylcholine predict development of stroke in a population-based study from northern Sweden

R Fiskesund, B Stegmayr, G Hallmans, M Vikström… - Stroke, 2010 - Am Heart Assoc
Background and Purpose—Natural immunoglobulin M antibodies specific for
phosphorylcholine (anti-PC) have been implicated in atherosclerosis. We have shown …

Low levels of IgM antibodies against phosphorylcholine—a potential risk marker for ischemic stroke in men

BG Sjöberg, J Su, I Dahlbom, H Grönlund, M Wikström… - Atherosclerosis, 2009 - Elsevier
BACKGROUND: Natural antibodies specific for phosphorylcholine (anti-PC) have been
implicated as protective factors in atherosclerosis. We herein determined the relationship …

Low levels of IgM antibodies against phosphorylcholine predict development of acute myocardial infarction in a population-based cohort from northern Sweden

H Grönlund, G Hallmans, JH Jansson… - European Journal of …, 2009 - academic.oup.com
Objective Phosphorylcholine (PC) is one important epitope on oxidized low-density
lipoprotein that may play an important role by contributing to the atherogenicity of oxidized …

Antibodies against phosphorylcholine among New Guineans compared to Swedes: an aspect of the hygiene/missing old friends hypothesis

J Frostegård, WJ Tao, L Råstam… - Immunological …, 2017 - Taylor & Francis
Background: We here study antibodies against phosphorylcholine (anti-PC) which we
reported to be inversely associated with atherosclerosis, cardiovascular disease (CVD), and …

[HTML][HTML] Atheroprotective natural anti-phosphorylcholine antibodies of IgM subclass are decreased in Swedish controls as compared to non-westernized individuals …

J Frostegård, WJ Tao, A Georgiades, L Råstam… - Nutrition & …, 2007 - Springer
Objective To determine the importance of IgM antibodies against phosphorylcholine (aPC),
a novel protective factor for cardiovascular disease (CVD), in a population with a non …

Low level natural antibodies against phosphorylcholine: a novel risk marker and potential mechanism in atherosclerosis and cardiovascular disease

J Frostegård - Clinical immunology, 2010 - Elsevier
Atherosclerosis is an inflammatory condition characterised by an abundance of activated
immunocompetent cells in plaques which cause cardiovascular disease (CVD) when they …

Low levels of IgM antibodies against phosphorylcholine are associated with fast carotid intima media thickness progression and cardiovascular risk in men

B Gigante, K Leander, M Vikström, D Baldassarre… - Atherosclerosis, 2014 - Elsevier
Abstract Objective Low levels of IgM anti-phosphorylcholine (anti-PC) increase the risk of
cardiovascular events (CVE). Here we investigate the association of low anti-PC with the …

Natural antibodies against phosphorylcholine in cardiovascular disease

U De Faire, J Frostegård - Annals of the New York Academy of …, 2009 - Wiley Online Library
Atherosclerosis is a chronic inflammatory disease characterized by the presence of activated
immune‐competent cells in the lesions, producing mainly proinflammatory cytokines …

Low levels of IgM antibodies to phosphorylcholine predict cardiovascular disease in 60-year old men: effects on uptake of oxidized LDL in macrophages as a potential …

U de Faire, J Su, X Hua, A Frostegård, M Halldin… - Journal of …, 2010 - Elsevier
OBJECTIVE: We here determine the role of IgM antibodies against phosphorylcholine (anti-
PC) in prediction of cardiovascular disease (CVD) and on macrophage uptake of Oxidized …

Antibodies against phosphorylcholine and protection against atherosclerosis, cardiovascular disease and chronic inflammation

J Frostegård - Expert Review of Clinical Immunology, 2022 - Taylor & Francis
Introduction Chronic inflammatory diseases include cardiovascular disease (CVD),
atherosclerosis, rheumatic and autoimmune diseases, and others, constituting a large part of …