Clinical pharmacokinetics of nebivolol: a systematic review
Nebivolol is a beta-1 receptor blocker used to treat hypertension, heart failure, erectile
dysfunction, vascular disease, and diabetes mellitus. This review investigated the data …
dysfunction, vascular disease, and diabetes mellitus. This review investigated the data …
Nebivolol and incident cardiovascular events in hypertensive patients compared with nonvasodilatory beta blockers
DM Huck, MA Rosenberg, BL Stauffer - Journal of Hypertension, 2022 - journals.lww.com
Objective: Nonvasodilatory beta blockers are associated with inferior cardiovascular event
reduction compared with other antihypertensive classes, and there is uncertainty about first …
reduction compared with other antihypertensive classes, and there is uncertainty about first …
Comparative assessment of antihypertensive efficacy of DL-nebivolol and D-nebivolol in patients with confirmed mild to moderate hypertension
Y Lacourcière, L Poirier, J Lefebvre… - Journal of …, 1995 - journals.lww.com
We compared the antihypertensive activity of DL-and D-nebivolol in patients with essential
hypertension on clinic and 24-h ambulatory blood pressure (BP) and during dynamic …
hypertension on clinic and 24-h ambulatory blood pressure (BP) and during dynamic …
[HTML][HTML] Combining other antihypertensive drugs with β-blockers in hypertension: a focus on safety and tolerability
TR Richards, SW Tobe - Canadian Journal of Cardiology, 2014 - Elsevier
Combining multiple classes of antihypertensive drugs together is one of the most important
factors for achieving blood pressure control in most hypertensive patients. The benefits of …
factors for achieving blood pressure control in most hypertensive patients. The benefits of …
Long-term safety of nebivolol and valsartan combination therapy in patients with hypertension: an open-label, single-arm, multicenter study
JM Neutel, TD Giles, H Punzi, RJ Weiss, H Li… - Journal of the American …, 2014 - Elsevier
Long–term safety of a free–tablet combination of nebivolol and valsartan was assessed in a
Phase III, open–label trial (NCT01415505). Adults with hypertension entered a 4–week …
Phase III, open–label trial (NCT01415505). Adults with hypertension entered a 4–week …
The combination of nebivolol plus pravastatin is associated with a more beneficial metabolic profile compared to that of atenolol plus pravastatin in hypertensive …
E Rizos, E Bairaktari, A Kostoula… - Journal of …, 2003 - journals.sagepub.com
Nebivolol, a selective β1-lipophilic blocker, achieves blood pressure control by modulating
nitric oxide release in addition to b-blockade. This dual mechanism of action could result in …
nitric oxide release in addition to b-blockade. This dual mechanism of action could result in …
[PDF][PDF] Nebivolol-pharmacological aspects
GN Sahana, N Sarala, TN Kumar - Int J Biol Med Res, 2011 - Citeseer
Nebivolol is a beta blocker with a unique function which distinguishes it from other beta
blockers. It increases the release of nitric oxide (NO) which produces vasodilatation and …
blockers. It increases the release of nitric oxide (NO) which produces vasodilatation and …
Nebivolol for the treatment of heart failure
AS Dery, LA Hamilton, JA Starr - American Journal of Health …, 2011 - academic.oup.com
Purpose The pharmacology, pharmacokinetics, efficacy, safety, and place in therapy of
nebivolol are reviewed. Summary Nebivolol, a third-generation, highly β1-specific β-blocker …
nebivolol are reviewed. Summary Nebivolol, a third-generation, highly β1-specific β-blocker …
Metabolic and antihypertensive effects of nebivolol and atenolol in normometabolic patients with mild-to-moderate hypertension
Y Pesant, J Marc-Aurèle, P Bielmann… - American journal of …, 1999 - journals.lww.com
This was a double-blind, randomized, two-center, active-controlled, prospective, parallel
study designed to evaluate the effects of nebivolol at daily doses of 5 mg on lipid and …
study designed to evaluate the effects of nebivolol at daily doses of 5 mg on lipid and …
Nebivolol: the somewhat-different β-adrenergic receptor blocker
Although its clinical use in Europe dates almost 10 years, nebivolol is a β-blocker that has
been only recently introduced in the US market. Like carvedilol, nebivolol belongs to the …
been only recently introduced in the US market. Like carvedilol, nebivolol belongs to the …