Genotypic and phenotypic analysis of familial male breast cancer shows under representation of the HER2 and basal subtypes in BRCA-associated carcinomas
S Deb, N Jene, CF investigators, SB Fox - BMC cancer, 2012 - Springer
Background Male breast cancer (MBC) is an uncommon and relatively uncharacterised
disease accounting for< 1% of all breast cancers. A significant proportion occurs in families …
disease accounting for< 1% of all breast cancers. A significant proportion occurs in families …
BRCA1/BRCA2 mutation status and clinical-pathologic features of 108 male breast cancer cases from Tuscany: a population-based study in central Italy
Background Male breast cancer (MBC) is a rare and scarcely investigated disease. The
strongest genetic risk factor for MBC is represented by inherited BRCA2 mutations, whereas …
strongest genetic risk factor for MBC is represented by inherited BRCA2 mutations, whereas …
Phenotypic features and genetic characterization of male breast cancer families: identification of two recurrent BRCA2 mutations in north-east of Italy
GM Miolo, LD Puppa, M Santarosa, C De Giacomi… - BMC cancer, 2006 - Springer
Background Breast cancer in men is an infrequent occurrence, accounting for~ 1% of all
breast tumors with an incidence of about 1: 100,000. The relative rarity of male breast cancer …
breast tumors with an incidence of about 1: 100,000. The relative rarity of male breast cancer …
Identification of a new BRCA2 large genomic deletion associated with high risk male breast cancer
ARS Timoteo, BM Albuquerque, PPP Moura… - Hereditary Cancer in …, 2015 - Springer
Background Male breast cancer (MBC) is an uncommon disease that has been the focus of
limited research. It is estimated that approximately 10% of men with breast cancer have a …
limited research. It is estimated that approximately 10% of men with breast cancer have a …
Mutational profiling of familial male breast cancers reveals similarities with luminal A female breast cancer with rare TP53 mutations
Background: Male breast cancer (MBC) is still poorly understood with a large proportion
arising in families with a history of breast cancer. Genomic studies have focused on germline …
arising in families with a history of breast cancer. Genomic studies have focused on germline …
Male breast cancer: results of the application of multigene panel testing to an Italian cohort of patients
Male breast cancer (MBC) is a rare tumor, accounting for less than 1% of all breast cancers.
In MBC, genetic predisposition plays an important role; however, only a few studies have …
In MBC, genetic predisposition plays an important role; however, only a few studies have …
Somatic genetic alterations in BRCA2‐associated and sporadic male breast cancer
M Tirkkonen, T Kainu, N Loman… - Genes …, 1999 - Wiley Online Library
The genetic changes underlying the development and progression of male breast cancer
are poorly understood. Germline BRCA2 mutations account for a significant part of male …
are poorly understood. Germline BRCA2 mutations account for a significant part of male …
Male breast cancer: from molecular genetics to clinical management
M Pensabene, C Von Arx, M De Laurentiis - Cancers, 2022 - mdpi.com
Simple Summary Male breast cancer (MBC) is a rare disease. Genetic factors predispose to
male breast cancer. Germline and/or genetic and/or epigenetic alterations at the somatic …
male breast cancer. Germline and/or genetic and/or epigenetic alterations at the somatic …
Clinical and pathologic characteristics of BRCA-positive and BRCA-negative male breast cancer patients: results from a collaborative multicenter study in Italy
L Ottini, V Silvestri, P Rizzolo, M Falchetti… - Breast cancer research …, 2012 - Springer
Recently, the number of studies on male breast cancer (MBC) has been increasing.
However, as MBC is a rare disease there are difficulties to undertake studies to identify …
However, as MBC is a rare disease there are difficulties to undertake studies to identify …
Male breast cancer: a single-institution clinicopathologic and immunohistochemical study
KM Serdy, JP Leone, DJ Dabbs… - American Journal of …, 2017 - academic.oup.com
Objectives: A clinicopathologic study with an emphasis on tumor immunohistochemical
profile is presented. Methods: Sixty-one cases of male invasive breast cancers were studied …
profile is presented. Methods: Sixty-one cases of male invasive breast cancers were studied …