[HTML][HTML] Reciprocal interactions between osteoclasts and nociceptive sensory neurons in bone cancer pain

AS Andriessen, CR Donnelly, RR Ji - Pain Reports, 2021 - journals.lww.com
Many common cancers such as breast, prostate, and lung cancer metastasize to bones at
advanced stages, producing severe pain and functional impairment. At present, the current …

Pain and nociception: mechanisms of cancer-induced bone pain

S Falk, AH Dickenson - Journal of clinical oncology, 2014 - ascopubs.org
Cancer pain, especially pain caused by metastasis to bone, is a severe type of pain, and
unless the cause and consequences can be resolved, the pain will become chronic. As …

A mechanism‐based understanding of bone cancer pain

PW Mantyh - Pathological Pain: From Molecular to Clinical …, 2004 - Wiley Online Library
Although bone cancer pain can be severe and is relatively common, as it frequently arises
from metastases from breast, prostate and lung tumours, relatively little is known about the …

Bone cancer pain: causes, consequences, and therapeutic opportunities

P Mantyh - PAIN®, 2013 - Elsevier
Common cancers, including cancers of the breast, lung, and prostate, frequently metastasize
to multiple bones where they can cause significant and life-altering pain. Similar to cancer …

Crosstalk between sensory nerves and cancer in bone

T Yoneda, M Hiasa, T Okui - Current osteoporosis reports, 2018 - Springer
Abstract Purpose of Review Sensory nerves (SNs) richly innervate bone and are a
component of bone microenvironment. Cancer metastasis in bone, which is under the …

Bone cancer pain

JM Jimenez‐Andrade, WG Mantyh… - Annals of the New …, 2010 - Wiley Online Library
In the United States, cancer is the second most common cause of death and it is expected
that about 562,340 Americans will have died of cancer in 2009. Bone cancer pain is …

Cancer–nerve interplay in cancer progression and cancer-induced bone pain

T Yoneda, M Hiasa, T Okui, K Hata - Journal of Bone and Mineral …, 2023 - Springer
Introduction Cancer-induced bone pain (CIBP) is one of the most common and debilitating
complications associated with bone metastasis. Although our understanding of the precise …

[HTML][HTML] Sensory nerves: A driver of the vicious cycle in bone metastasis?

T Yoneda, M Hiasa, T Okui, K Hata - Journal of bone oncology, 2021 - Elsevier
Bone is one of the preferential target organs of cancer metastasis. Bone metastasis is
associated with various complications, of which bone pain is most common and debilitating …

Mechanisms that generate and maintain bone cancer pain

PW Mantyh, SP Hunt - Osteoarthritic Joint Pain: Novartis …, 2004 - Wiley Online Library
Although bone cancer pain can be severe and is relatively common, as it frequently arises
from metastases from breast, prostate, and lung tumours, very little is known about the basic …

Cancer-induced bone pain: Mechanisms and models

AN Lozano-Ondoua, AM Symons-Liguori… - Neuroscience …, 2013 - Elsevier
Cancerous cells can originate in a number of different tissues such as prostate, breast and
lung, but often go undetected and are non-painful. Many types of cancers have a propensity …