[HTML][HTML] miR-146a plasma levels are not altered in Alzheimer's disease but correlate with age and illness severity
E Maffioletti, E Milanesi, A Ansari, O Zanetti… - Frontiers in Aging …, 2020 - frontiersin.org
miR-146a is a microRNA (miRNA) involved in neuroinflammation and aging; alterations in
its expression were described in Alzheimer's disease (AD). However, most of the studies …
its expression were described in Alzheimer's disease (AD). However, most of the studies …
MicroRNA-138 overexpression alters Aβ42 levels and behavior in wildtype mice
E Boscher, C Goupil, S Petry, R Keraudren… - Frontiers in …, 2021 - frontiersin.org
Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by
changes in cognitive and behavioral functions. With the exception or rare mutations in PSEN …
changes in cognitive and behavioral functions. With the exception or rare mutations in PSEN …
MicroRNA-181 promotes synaptogenesis and attenuates axonal outgrowth in cortical neurons
A Kos, N Olde Loohuis, J Meinhardt… - Cellular and molecular …, 2016 - Springer
MicroRNAs (miRs) are non-coding gene transcripts abundantly expressed in both the
developing and adult mammalian brain. They act as important modulators of complex gene …
developing and adult mammalian brain. They act as important modulators of complex gene …
Exploring the impact of miR-128 in inflammatory diseases: A comprehensive study on autoimmune diseases
Abstract microRNAs (miRNAs) play a crucial role in various biological processes, including
immune system regulation, such as cell proliferation, tolerance (central and peripheral), and …
immune system regulation, such as cell proliferation, tolerance (central and peripheral), and …
[HTML][HTML] MicroRNA-124: a key player in microglia-mediated inflammation in neurological diseases
J Zhao, Z He, J Wang - Frontiers in cellular neuroscience, 2021 - frontiersin.org
Neurological disorders are mainly characterized by progressive neuron loss and
neurological deterioration, which cause human disability and death. However, many types of …
neurological deterioration, which cause human disability and death. However, many types of …
Role of microRNAs in the regulation of innate immune cells under neuroinflammatory conditions
AL Cardoso, JR Guedes, MCP De Lima - Current opinion in pharmacology, 2016 - Elsevier
Highlights•Transcriptome studies suggest miRNAs can be used as microglia phenotype
markers.•MiR-124 regulates the quiescent state of microglia in the brain.•The immune role of …
markers.•MiR-124 regulates the quiescent state of microglia in the brain.•The immune role of …
[PDF][PDF] MicroRNA-155 promotes autoimmune inflammation by enhancing inflammatory T cell development
Mammalian noncoding microRNAs (miRNAs) are a class of gene regulators that have been
linked to immune system function. Here, we have investigated the role of miR-155 during an …
linked to immune system function. Here, we have investigated the role of miR-155 during an …
miR-132/212 knockout mice reveal roles for these miRNAs in regulating cortical synaptic transmission and plasticity
J Remenyi, MWM van den Bosch, O Palygin, RB Mistry… - PloS one, 2013 - journals.plos.org
miR-132 and miR-212 are two closely related miRNAs encoded in the same intron of a small
non-coding gene, which have been suggested to play roles in both immune and neuronal …
non-coding gene, which have been suggested to play roles in both immune and neuronal …
Loss of the neurodevelopmental disease-associated gene miR-146a impairs neural progenitor differentiation and causes learning and memory deficits
J Fregeac, S Moriceau, A Poli, LS Nguyen, F Oury… - Molecular autism, 2020 - Springer
Background Formation and maintenance of appropriate neural networks require tight
regulation of neural stem cell proliferation, differentiation, and neurogenesis. microRNAs …
regulation of neural stem cell proliferation, differentiation, and neurogenesis. microRNAs …
Early miR-155 upregulation contributes to neuroinflammation in Alzheimer's disease triple transgenic mouse model
JR Guedes, CM Custodia, RJ Silva… - Human molecular …, 2014 - academic.oup.com
MicroRNAs (miRNAs) have emerged as a class of small, endogenous, regulatory RNAs that
exhibit the ability to epigenetically modulate the translation of mRNAs into proteins. This …
exhibit the ability to epigenetically modulate the translation of mRNAs into proteins. This …