AIM: To investigate the association between epidermal growth factor (EGF)+ 61A/G
polymorphism and susceptibility to gastric cancer, through a cross-sectional study …

Background Epidermal growth factor (EGF) plays a pivotal role in cell proliferation,
differentiation, and tumorigenesis of epithelial tissues. Variation of the EGF+ 61A/G …

Previous studies suggested an association between the EGF+ 61 A> G polymorphism and
susceptibility to gastric cancer, but the results have been inconsistent. To draw a more …

The etiology of gastric cancer is not well-understood. Epidermal growth factor (EGF)
transduces growth signals to mitogen-activated protein kinase via RAS and BRAF, and …

Background: Numerous studies have investigated the risk of cancer associated with the
polymorphism of epidermal growth factor (EGF) 61A> G, but the results have been …

Emerging evidences from preclinical and clinical studies have shown that epidermal growth
factor (EGF) has some effectiveness against endogenously arising carcinogenesis …

Results The A allele of EGF+ 61 G/A was less frequently in gastric cancer patients than in
controls (OR= 0.73, 95% CI= 0.55-0.95, p= 0.02). The A allele frequency was also …

Epidermal growth factor (EGF), a ligand of the EGF receptor, plays a critical role in the
development of gastric cancer. Genetic variants in its promoter region may influence …

Background: Epidermal growth factor (EGF) induces various biological signaling pathways,
including proliferation and differentiation and it is the natural ligand of the epidermal growth …

Objective: Epidermal growth factor (EGF) has many biological functions and plays an
important role in the progression of various tumors including gastric cancer. An AG single …