Abstract Background The symptoms for Major Depression (MD) defined in the DSM-5 differ
markedly from symptoms assessed in common rating scales, and the empirical question …

Background The DSM-5 encompasses a wide range of symptoms for Major Depressive
Disorder (MDD). Symptoms are commonly added up to sum-scores, and thresholds …

Importance Major depressive disorder (MDD) is a heterogeneous condition in terms of
symptoms, course, and underlying disease mechanisms. Current classifications do not …

Abstract Introduction We compared DSM-IV criteria for major depression (MD) with clinically
selected non-DSM criteria in their ability to represent clinical features of depression. Method …

To explain the overt heterogeneous nature of major depressive disorder (MDD), it could be
valuable to focus on individual symptoms [1]. Recent research, for example, showed that …

Background Depression severity is assessed in numerous research disciplines, ranging
from the social sciences to genetics, and used as a dependent variable, predictor, covariate …

Background In recent years, researchers have used various techniques to elucidate the
heterogeneity in depressive symptoms. This study seeks to resolve the extent to which …

BackgroundThe DSM-IV symptomatic criteria for major depression (MD) derive primarily
from clinical experience with modest empirical support. MethodThe sample studied included …

Importance Depressive severity is typically measured according to total scores on
questionnaires that include a diverse range of symptoms despite convincing evidence that …

Background: Comorbid anxiety symptoms are highly prevalent and closely linked with
poorer treatment outcomes, chronicity, and hospitalization in major depressive disorder …