From lamins to lamina: a structural perspective
M Zwerger, O Medalia - Histochemistry and cell biology, 2013 - Springer
Lamin proteins are the major constituents of the nuclear lamina, a proteinaceous network
that lines the inner nuclear membrane. Primarily, the nuclear lamina provides structural …
that lines the inner nuclear membrane. Primarily, the nuclear lamina provides structural …
Lamina-independent lamins in the nuclear interior serve important functions
T Dechat, K Gesson, R Foisner - Cold Spring Harbor …, 2010 - symposium.cshlp.org
Nuclear lamins were originally described as the main constituents of the nuclear lamina, a
filamentous meshwork closely associated with the inner nuclear membrane. However, within …
filamentous meshwork closely associated with the inner nuclear membrane. However, within …
Insight into the functional organization of nuclear lamins in health and disease
Lamins are the main component of the nuclear lamina, a protein meshwork at the inner
nuclear membrane which primarily provide mechanical stability to the nucleus. Lamins, type …
nuclear membrane which primarily provide mechanical stability to the nucleus. Lamins, type …
Emerging perspectives on laminopathies
G Lattanzi, S Benedetti, MR D'Apice… - Cell Health and …, 2016 - Taylor & Francis
Laminopathies are a group of inherited disorders caused by mutations in the lamin A/C
gene, and can affect diverse organs or tissues, or can be systemic, causing premature …
gene, and can affect diverse organs or tissues, or can be systemic, causing premature …
Lamins: the structure and protein complexes
Y Gruenbaum, O Medalia - Current opinion in cell biology, 2015 - Elsevier
Lamins are nuclear intermediate filament (IF) proteins. They assemble to fibrous structures
that are positioned between the inner nuclear membrane and the peripheral chromatin. A …
that are positioned between the inner nuclear membrane and the peripheral chromatin. A …
[HTML][HTML] A-type lamin networks in light of laminopathic diseases
S Vlcek, R Foisner - Biochimica et Biophysica Acta (BBA)-Molecular Cell …, 2007 - Elsevier
Lamins are major structural components of the lamina providing mechanical support for the
nuclear envelope in vertebrates. A subgroup of lamins, the A-type lamins, are only …
nuclear envelope in vertebrates. A subgroup of lamins, the A-type lamins, are only …
Nuclear lamins: thin filaments with major functions
R de Leeuw, Y Gruenbaum, O Medalia - Trends in cell biology, 2018 - cell.com
The nuclear lamina is a nuclear peripheral meshwork that is mainly composed of nuclear
lamins, although a small fraction of lamins also localizes throughout the nucleoplasm …
lamins, although a small fraction of lamins also localizes throughout the nucleoplasm …
Laminopathic mutations interfere with the assembly, localization, and dynamics of nuclear lamins
N Wiesel, A Mattout, S Melcer… - Proceedings of the …, 2008 - National Acad Sciences
Lamins are nuclear intermediate filament proteins and the major building blocks of the
nuclear lamina. Besides providing nuclear shape and mechanical stability, lamins are …
nuclear lamina. Besides providing nuclear shape and mechanical stability, lamins are …
Nuclear lamins, diseases and aging
Nuclear lamins are type V intermediate filament proteins. They are the major building blocks
of the peripheral nuclear lamina, a complex meshwork of proteins underlying the inner …
of the peripheral nuclear lamina, a complex meshwork of proteins underlying the inner …
Laminopathies
JLV Broers, CJ Hutchison… - The Journal of …, 2004 - Wiley Online Library
Nuclear lamins form a fibrous nucleoskeletal network of intermediate‐sized filaments that
underlies the inner nuclear membrane. It associates with this membrane through …
underlies the inner nuclear membrane. It associates with this membrane through …