The dopamine D3 receptor (D3R) has been implicated in schizophrenia, drug addiction,
depression and Parkinson's disease. The D3R is localized post-synaptically on nucleus …

Polymorphic variants of the dopamine D4 receptor gene (DRD4) have been repeatedly
associated with numerous neuropsychiatric disorders. Yet, the functional role of the D4 …

The D3 dopamine receptor is postulated to play an important role in the regulation of
neurotransmitter secretion at both pre-and postsynaptic terminals. However, this hypothesis …

Bacteria artificial chromosome (BAC) transgenic mice expressing the reporter protein
enhanced green fluorescent protein (EGFP) under the control of the D1 and D2 dopamine …

Summary The D1-and D2-dopamine receptors (D1R and D2R), which signal through G s
and G i, respectively, represent the principal stimulatory and inhibitory dopamine receptors …

Accurate control of dopamine levels and/or the resulting dopamine–receptor interaction is
essential for brain function. Indeed, several human neurological and psychiatric disorders …

The widespread biological actions of the neurotransmitter dopamine (DA) are mediated by
two classes of receptor, the D1 class (D1 and D5) and the D2 class (D2, D3, and D4), which …

The description of new dopamine (DA) receptor subtypes, D1-(D1 and D5) and D2-like
(D2A, D2B, D3, D4), has given an impetus to DA research. While selective agonists and …

Several lines of evidence suggest the existence of multiple dopamine receptor subtypes,
referred to as D1 and D2. The present study examines the distribution of these dopamine …

Dysregulation of dopamine transmission is thought to contribute to schizophrenic psychosis
and drug dependence. Dopamine release is regulated by D2 dopamine autoreceptors, and …