The two most striking features of Alzheimer disease are (i) the multitude of abnormalities
affecting essentially every system and (ii) the strict age dependence. Recent work suggests …

Research in Alzheimer disease has recently demonstrated compelling evidence on the
importance of oxidative processes in its pathogenesis. Cellular changes show that oxidative …

It has now been established through multiple lines of evidence that oxidative stress is an
early event in Alzheimer's disease, occurring prior to the canonical cytopathology. Thus …

Recent evidence in the field of Alzheimer disease research has highlighted the importance
of oxidative processes in its pathogenesis. Examination of cellular changes shows that …

Oxidative stress is a key factor involved in the development and progression of Alzheimer's
disease, and it is well documented that free radical oxidative damage, particularly of …

Oxidative balance is emerging as an important issue in understanding the pathogenesis of
Alzheimer's disease. Examination of Alzheimer's disease brain has demonstrated a great …

Over the past decade, oxidative stress has been established as the earliest cytological
feature of Alzheimer disease and an attractive therapeutic target. The major challenges now …

Oxidative stress occurs early in the progression of Alzheimer disease, significantly before
the development of the pathologic hallmarks, neurofibrillary tangles and senile plaques. All …

Alzheimer's disease (AD) is the most common form of neurodegenerative disease
associated with dementia in the elderly. Although the initiating events are still unknown, it is …

Over the past decade, the study of oxidative stress in relation to the pathogenesis of
Alzheimer's and other neurodegenerative diseases has been transformed from an esoteric …