An HLA-DR3 association with membranous nephropathy (MN) was described in 1979 and
additional evidence for a genetic component to MN was suggested in 1984 in reports of …

The M-type receptor for phospholipase A2 (PLA2R1) is the major target antigen in idiopathic
membranous nephropathy (iMN). Our recent genome-wide association study showed that …

Background Antibodies to M-type phospholipase A2 receptor (PLA2R) correlate with clinical
activity of primary membranous nephropathy (PMN). Risk alleles in PLA2R1 and HLA-DQA1 …

Idiopathic membranous nephropathy (MN) is associated with HLA; however, the HLA allele
involved remains unknown. To identify the HLA risk alleles associated with phospholipase …

Membranous nephropathy (MN) is the most common primary glomerular disease (PGD) in
the world. Currently, MN still lacks specific diagnostic markers and effective treatment …

Background: Membranous nephropathy (MN) is a common cause of nephrotic syndrome in
adults. Previous genome-wide association studies (GWAS) of 300 000 genotyped variants …

Antibodies to the phospholipase A2 receptor 1 (PLA2R1) have been reported in 70% of
cases of idiopathic membranous nephropathy (IMN). The genetic susceptibility of IMN has …

Primary (or idiopathic) membranous nephropathy is an organ-specific autoimmune disease
in which circulating antibodies to a conformation-dependent epitope in the target antigen …

Background: The phospholipase A2 receptor (PLA2R) is a major antigen found in patients
with idiopathic membranous nephropathy (MN). The relationship of genetic polymorphisms …

Lessons from an animal model that faithfully resembles human membranous nephropathy
(MN) have informed our understanding of the pathogenesis of this organ-specific …