There is evidence that cannabinoids modulate the reuptake of some neurotransmitters in the
central nervous system. In this study, we investigated the effects of the synthetic cannabinoid …

We have examined the effect of Delta1-tetrahydrocannabinol (delat1-THC) and 12 of its
derivatives on the uptake of 3H-labeled norepinephrine (NE), dopamine (DA), serotonin (5 …

Abstract Δ 1-Tetrahydrocannabinol (Δ 1-THC) and cannabidiol (CBD), a psychoactive and a
nonpsychoactive constituent of marijuana respectively, inhibit the uptake of 3 H-labelled …

In vitro effects of delta 9-tetrahydrocannabinol (delta 9-THC), delta 8-tetrahydrocannabinol
(delta 8-THC), cannabinol (CBN) and cannabidiol (CBD) have been studied on the uptake …

Guinea-pig hippocampal slices preincubated with [3 H] noradrenaline were superfused with
medium containing desipramine and rauwolscine and rat striatal slices preincubated with [3 …

Adenosine, dopamine and endocannabinoids strictly modulate the release of one another in
the dorsolateral striatum thereby controlling synaptic plasticity. As a second level of …

We previously reported that administration of the synthetic cannabinoid agonist WIN 55,212‐
2 causes an increase in norepinephrine (NE) efflux in the frontal cortex (FC). The present …

A brain constituent, the N-amide derivative of arachidonic acid, termed anandamide, has
been recently proposed as a possible endogenous ligand for the cannabinoid receptor. The …

We have used an ex vivo binding assay in the mouse to evaluate the brain penetration of
cannabinoid receptor ligands. After intraperitoneal or oral administration, the …

Cannabinoid receptors and their endogenous ligands have been recently identified in the
brain as potent inhibitors of neurotransmitter release. Here we show that, in a rat model of …