Oxidized low density lipoproteins: the bridge between atherosclerosis and autoimmunity. Possible implications in accelerated atherosclerosis and for immune …

CF Suciu, M Prete, P Ruscitti, E Favoino… - Autoimmunity …, 2018 - Elsevier
Atherosclerotic vasculopathy is a multifactorial process causing vessels damage and
cardiovascular diseases, the leading causes of death worldwide. Atherosclerotic plaque is …

Accelerated atherosclerosis, immune response and autoimmune rheumatic diseases

LJ Jara, G Medina, O Vera-Lastra, MC Amigo - Autoimmunity reviews, 2006 - Elsevier
Atherosclerosis (AT) is a chronic autoimmune inflammatory disease, characterized by
lipoproteins metabolism alteration leading to formation of pro-inflammatory and pro …

Autoimmunity, oxidized LDL and cardiovascular disease

J Frostegård - Autoimmunity reviews, 2002 - Elsevier
Atherosclerosis is the major cause of cardiovascular disease (CVD) and in addition to
established risk factors as smoking, hypertension, diabetes and dyslipidemia, inflammation …

Is atherosclerosis an autoimmune disease?

E Matsuura, F Atzeni, P Sarzi-Puttini, M Turiel… - BMC medicine, 2014 - Springer
Immunologic research into pathogenic mechanisms operating in autoimmune-mediated
atherosclerosis initially focused on adaptive immunity. Current interest is directed to more …

Atherosclerosis: Beyond the lipid storage hypothesis. The role of autoimmunity

II Cinoku, CP Mavragani… - European Journal of …, 2020 - Wiley Online Library
Atherosclerosis has long been considered as a lipid storage disease. Recent data suggest
that autoimmune mechanisms seem to be involved in the pathophysiology of …

Oxidized low-density lipoprotein biomarkers in atherosclerosis

S Tsimikas - Current atherosclerosis reports, 2006 - Springer
The concept that the oxidation of lipoproteins is central in the pathogenesis of
atherosclerosis was first reported over 25 years ago, initially by in vitro studies and …

The endothelium: an interface between autoimmunity and atherosclerosis in systemic lupus erythematosus?

CB Narshi, IP Giles, A Rahman - Lupus, 2011 - journals.sagepub.com
Patients with systemic lupus erythematosus (SLE) have an increased risk of developing
cardiovascular disease (CVD). Traditional risk factors fail to fully explain all of this increased …

Oxidation of LDL and its clinical implication

E Matsuura, GRV Hughes, MA Khamashta - Autoimmunity reviews, 2008 - Elsevier
Oxidative modification of low-density lipoprotein (LDL) is one of the earliest events in
atherosclerosis. Oxidized LDL (oxLDL) represents a variety of modification of both lipid and …

The effects of lipid-lowering therapy on low-density lipoprotein auto-antibodies: relationship with low-density lipoprotein oxidation and plasma total antioxidant status

C Örem, A Örem, HA Uydu, S Çelik, C Erdöl… - Coronary artery …, 2002 - journals.lww.com
Background Oxidized low-density lipoprotein (Ox-LDL) is believed to play an important role
in the progression of atherosclerosis. Oxidative modification of low-density lipoprotein (LDL) …

Autoantibodies against oxidized low density lipoproteins in patients with stable angina, unstable angina or peripheral vascular disease; pathophysiological …

C Monaco, F Crea, G Niccoli, F Summaria… - European Heart …, 2001 - academic.oup.com
Background Antibody antioxidized low density lipoproteins (oxLDL) might play a role both in
atherogenesis and in the pathogenesis of acute coronary syndromes. Methods and Results …