Valsartan, an angiotensin II receptor antagonist, is widely used to treat high blood pressure
in the clinical setting. However, its poor water solubility results in the low oral bioavailability …

Valsartan is an effective, highly selective and orally active antihypertensive exhibiting low
aqueous solubility and poor dissolution that limit its absorption resulting in low …

The present studies entail formulation development of novel solid self-nanoemulsifying drug
delivery systems (S-SNEDDS) of valsartan with improved oral bioavailability, and evaluation …

The main objective this study is to prepare and evaluate the selfnanoemulsifying drug
delivery (SNEDDS) system in order to achieve a better dissolution rate of a poorly water …

The main objective of present work was to prepare a solid SEDDS for enhancement of oral
bioavailability of Valsartan, poorly water soluble drug. The solubility of the drug was …

During the last decades, much attention has been focused on SNEDDS approach to resolve
concerns of BCS II class drugs with accentuation on upgrading the solubility and …

Valsartan is an angiotensin converting enzyme inhibitor which is poorly soluble in water,
which leads to low oral bioavailability (19-25%). For this reason, the study target was to …

A novel, supersaturable self-microemulsifying drug delivery system (S-SMEDDS) was
successfully formulated to enhance the dissolution and oral absorption of valsartan (VST), a …

Antihypertensive treatment reduces the risk of cardiovascular complications in patients with
high mortality with hypertension. Valsartan is highly selective antihypertensive that is rapidly …

Candesartan cilexetil is the prodrug of candesartan, a selective angiotensin II receptor
antagonist, used in the management of hypertension and heart failure. It is characterized by …