The psychosis high-risk state: a comprehensive state-of-the-art review
Context During the past 2 decades, a major transition in the clinical characterization of
psychotic disorders has occurred. The construct of a clinical high-risk (HR) state for …
psychotic disorders has occurred. The construct of a clinical high-risk (HR) state for …
Progression from being at-risk to psychosis: next steps
Over the past 20 years there has been a great deal of research into those considered to be
at risk for developing psychosis. Much has been learned and studies have been …
at risk for developing psychosis. Much has been learned and studies have been …
At risk for schizophrenic or affective psychoses? A meta-analysis of DSM/ICD diagnostic outcomes in individuals at high clinical risk
P Fusar-Poli, A Bechdolf, MJ Taylor… - Schizophrenia …, 2013 - academic.oup.com
Background The clinical high-risk state for psychosis (HRP) is associated with an enhanced
probability of developing a psychotic episode over a relatively short period of time. However …
probability of developing a psychotic episode over a relatively short period of time. However …
Heterogeneity of psychosis risk within individuals at clinical high risk: a meta-analytical stratification
P Fusar-Poli, M Cappucciati, S Borgwardt… - JAMA …, 2016 - jamanetwork.com
Importance Individuals can be classified as being at clinical high risk (CHR) for psychosis if
they meet at least one of the ultra–high-risk (UHR) inclusion criteria (brief limited intermittent …
they meet at least one of the ultra–high-risk (UHR) inclusion criteria (brief limited intermittent …
Beyond the “at risk mental state” concept: transitioning to transdiagnostic psychiatry
PD McGorry, JA Hartmann, R Spooner… - World …, 2018 - Wiley Online Library
The “at risk mental state” for psychosis approach has been a catalytic, highly productive
research paradigm over the last 25 years. In this paper we review that paradigm and …
research paradigm over the last 25 years. In this paper we review that paradigm and …
Predicting psychosis: meta-analysis of transition outcomes in individuals at high clinical risk
Context A substantial proportion of people at clinical high risk of psychosis will develop a
psychotic disorder over time. However, the risk of transition to psychosis varies between …
psychotic disorder over time. However, the risk of transition to psychosis varies between …
Prevention of psychosis: advances in detection, prognosis, and intervention
Importance Detection, prognosis, and indicated interventions in individuals at clinical high
risk for psychosis (CHR-P) are key components of preventive psychiatry. Objective To …
risk for psychosis (CHR-P) are key components of preventive psychiatry. Objective To …
Is the clinical high-risk state a valid concept? Retrospective examination in a first-episode psychosis sample
Objective: One reason for worldwide interest in the clinical high-risk (CHR) state for
psychosis is its potential as a target for prevention. However, the feasibility and utility of early …
psychosis is its potential as a target for prevention. However, the feasibility and utility of early …
Lessons learned from the psychosis high-risk state: towards a general staging model of prodromal intervention
BackgroundThe past two decades have seen exponential clinical and research interest in
help-seeking individuals presenting with potentially prodromal symptoms for psychosis …
help-seeking individuals presenting with potentially prodromal symptoms for psychosis …
Probability of transition to psychosis in individuals at clinical high risk: an updated meta-analysis
Importance Estimating the current likelihood of transitioning from a clinical high risk for
psychosis (CHR-P) to psychosis holds paramount importance for preventive care and …
psychosis (CHR-P) to psychosis holds paramount importance for preventive care and …