Importance Estimating the current likelihood of transitioning from a clinical high risk for
psychosis (CHR-P) to psychosis holds paramount importance for preventive care and …

Abstract The Clinical High-Risk state for psychosis (CHR-P) paradigm was introduced about
2 decades ago. Over this period of time accumulating knowledge has been gained …

Background The clinical high risk (CHR) paradigm has facilitated research into the
underpinnings of help-seeking individuals at risk for developing psychosis, aiming at …

Prediction and prevention of negative clinical and functional outcomes represent the two
primary objectives of research conducted within the clinical high-risk for psychosis (CHR-P) …

After decades of research, schizophrenia and related psychotic disorders are still among the
most debilitating disorders in medicine. The chronic illness course in most individuals …

Background: The first rate-limiting step for improving outcomes of psychosis through
preventive interventions in people at clinical high risk for psychosis (CHR-P) is the ability to …

The validity and clinical utility of the concept of “clinical high risk”(CHR) for psychosis have
so far been investigated only in risk‐enriched samples in clinical settings. In this population …

Twenty percent of individuals at clinical high risk for psychosis (CHR-P) develop the disorder
within 2 years. Extensive research has explored the factors that differentiate those who …

Recent evidence has suggested that psychosis could develop not only in people at clinical
high risk for psychosis (CHR-P) but also in those with clinical risk syndromes for emergent …

The ideathat we can reduce the incidence of psychotic disorders through detection and
intervention in the prodromal stage of illness has generated increasing enthusiasm and …