Mouse models are important for pulmonary research to gain insight into structure and
function in normal and diseased states, thereby extending knowledge of human disease …

Micro-CT will have a profound influence on the accumulation of anatomical and
physiological phenotypic changes in natural and transgenetic mouse models. Longitudinal …

Thoracic imaging for small animals has emerged as an important tool for monitoring
pulmonary disease progression and therapy response in genetically engineered animals …

Animal models of lung disease are gaining importance in understanding the underlying
mechanisms of diseases such as emphysema and lung cancer. Micro-CT allows in vivo …

Computed tomography (CT) of the lung has made major advances in hardware and software
over the last decade. The human lung can now be imaged rapidly and volumetrically, with …

We present a highly automated approach to obtain detailed structural models of airway trees
from ex vivo porcine lung tissue imaged with a high resolution micro-CT scanner. Such …

Mouse models are becoming instrumental for the study of lung disease. Due to its resolution
and low cost, high resolution Computed Tomography (micro-CT) is a very adequate …

Utilizing micro-X-ray CT (μCT) imaging, we sought to generate an atlas of in vivo and
intact/ex vivo lungs from normal murine strains. In vivo imaging allows visualization of …

CT is superior to other imaging techniques for the study of lung diseases, as it can provide
excellent anatomic detail of various structures. Advances in CT technology have transformed …

Background In vivo high-resolution micro-computed tomography allows for longitudinal
image-based measurements in animal models of lung disease. The combination of …