Development of a renal microchip for in vitro distal tubule models
R Baudoin, L Griscom, M Monge… - Biotechnology …, 2007 - Wiley Online Library
Current developments in tissue engineering and microtechnology fields have allowed the
proposal of pertinent tools, microchips, to investigate in vitro toxicity. In the framework of the …
proposal of pertinent tools, microchips, to investigate in vitro toxicity. In the framework of the …
[HTML][HTML] Technology transfer of the microphysiological systems: a case study of the human proximal tubule tissue chip
C Sakolish, EJ Weber, EJ Kelly, J Himmelfarb… - Scientific reports, 2018 - nature.com
The adoption of a new technology into basic research, and industrial and clinical settings
requires rigorous testing to build confidence in the reproducibility, reliability, robustness, and …
requires rigorous testing to build confidence in the reproducibility, reliability, robustness, and …
[HTML][HTML] Mimicking the kidney: a key role in organ-on-chip development
R Paoli, J Samitier - Micromachines, 2016 - mdpi.com
Pharmaceutical drug screening and research into diseases call for significant improvement
in the effectiveness of current in vitro models. Better models would reduce the likelihood of …
in the effectiveness of current in vitro models. Better models would reduce the likelihood of …
Tissue engineering of a bioartificial renal tubule
SM MacKay, AJ Funke, DA Buffington, HD Humes - ASAIO journal, 1998 - journals.lww.com
Abstract Development of a bioartificial renal tubule with a confluent monolayer of renal
epithelial cells supported on a permeable synthetic surface may be the first step to further …
epithelial cells supported on a permeable synthetic surface may be the first step to further …
Design engineering of a bioartificial renal tubule cell therapy device
J Nikolovski, E Gulari, HD Humes - Cell transplantation, 1999 - journals.sagepub.com
The use of a bioartificial renal tubule device composed of renal proximal tubule cells grown
within a hollow fiber cartridge is a first step in engineering a bioartificial kidney to provide …
within a hollow fiber cartridge is a first step in engineering a bioartificial kidney to provide …
Trends in the development of microfluidic cell biochips for in vitro hepatotoxicity
Current developments in the technological fields of liver tissue engineering, bioengineering,
biomechanics, microfabrication and microfluidics have lead to highly complex and pertinent …
biomechanics, microfabrication and microfluidics have lead to highly complex and pertinent …
Micropattern-based platform as a physiologically relevant model to study epithelial morphogenesis and nephrotoxicity
M Bosch-Fortea, AE Rodriguez-Fraticelli, G Herranz… - Biomaterials, 2019 - Elsevier
Tubulogenesis in epithelial organs often initiates with the acquisition of apicobasal polarity,
giving rise to the formation of small lumens that expand and fuse to generate a single …
giving rise to the formation of small lumens that expand and fuse to generate a single …
[HTML][HTML] Tissue engineering of a bioartificial renal tubule assist device: in vitro transport and metabolic characteristics
HD Humes, SM Mackay, AJ Funke, DA Buffington - Kidney international, 1999 - Elsevier
Tissue engineering of a bioartificial renal tubule assist device: In vitro transport and
metabolic characteristics. Background Current renal substitution therapy for acute or chronic …
metabolic characteristics. Background Current renal substitution therapy for acute or chronic …
Kidney-on-a-chip technology for renal proximal tubule tissue reconstruction
TTG Nieskens, MJ Wilmer - European journal of pharmacology, 2016 - Elsevier
The renal proximal tubule epithelium is responsible for active secretion of endogenous and
exogenous waste products from the body and simultaneous reabsorption of vital compounds …
exogenous waste products from the body and simultaneous reabsorption of vital compounds …
Biology on a chip: microfabrication for studying the behavior of cultured cells
N Li, A Tourovskaia, A Folch - Critical Reviews™ in Biomedical …, 2003 - dl.begellhouse.com
The ability to culture cells in vitro has revolutionized hypothesis testing in basic cell and
molecular biology research and has become a standard methodology in drug screening and …
molecular biology research and has become a standard methodology in drug screening and …