The positive coreceptor function of complement receptor type 2 [CR2 (CD21)] on B cells is
generally accepted, although its role in the enhancement of antibody production had only …

The complement system—particularly component C3—has been demonstrated to be a key
link between innate and adaptive immunity. The trimolecular complex of complement …

Complement is an essential innate immune mechanism that recognizes and eradicates
microbes and associated toxins. In addition, complement receptors (CD21 and CD35) on B …

Abstract The complement receptor 3 (CR3; CD11b/CD18) is present exclusively on
leukocytes, particularly on NK cells, monocytes and polymorphonuclear neutrophils …

Before antigen-specific immunity arises, the complement system responds by activation
through the classical and/or alternative pathways leading to the covalent deposition of …

C3dg is a cleavage product of the C3 component of complement that can facilitate the
coligation of the complement receptor 2 (CR2/CD21) with the BCR via C3dg/Ag complexes …

The C3d fragment of complement component C3 has been shown to enhance immune
responses to antigens that lack T‐cell epitopes such as bacterial polysaccharides. C3d …

Complement receptors (CRs) CD21 and CD35 form a coreceptor with CD19 and CD81 on
murine B cells that when coligated with the B-cell receptor lowers the threshold of activation …

We found that transgenic (tg) mice stably expressing a bacterial artificial chromosome (BAC)-
derived human complement receptor type 2 (CR2/CD21) gene demonstrate B cell specific …

The role of complement in the regulation of T cell immunity has been highlighted recently by
several groups. We were prompted to reinvestigate the role of complement receptor type 1 …