[HTML][HTML] An overview of mammalian p38 mitogen-activated protein kinases, central regulators of cell stress and receptor signaling
The p38 family is a highly evolutionarily conserved group of mitogen-activated protein
kinases (MAPKs) that is involved in and helps co-ordinate cellular responses to nearly all …
kinases (MAPKs) that is involved in and helps co-ordinate cellular responses to nearly all …
p38 MAPK signalling cascades in inflammatory disease
E Herlaar, Z Brown - Molecular medicine today, 1999 - cell.com
Inflammatory mediators released during acute and chronic diseases activate multiple
intracellular signalling cascades including the mitogen-activated protein kinase (MAPK) …
intracellular signalling cascades including the mitogen-activated protein kinase (MAPK) …
[HTML][HTML] Non-classical p38 map kinase functions: cell cycle checkpoints and survival
TM Thornton, M Rincon - International journal of biological …, 2009 - ncbi.nlm.nih.gov
The p38 MAPK kinase pathway is activated in response to a wide range of cellular stress
stimuli and cytokines. Our understanding of the important functions of p38 MAPK in the …
stimuli and cytokines. Our understanding of the important functions of p38 MAPK in the …
The p38 MAP kinase pathway and its biological function
L New, J Han - Trends in cardiovascular medicine, 1998 - Elsevier
p38 is a mitogen-activated protein (MAP) kinase with structural and functional characteristics
that distinguish it from JNK and ERK MAP kinases. p38 activity is upregulated when cells are …
that distinguish it from JNK and ERK MAP kinases. p38 activity is upregulated when cells are …
Mitogen-activated protein kinases
S Arbabi, RV Maier - Critical care medicine, 2002 - journals.lww.com
The cellular control switches are regulated through an extensive network of interactive
intracellular signal transduction pathways, such as the mitogen-activated protein kinase …
intracellular signal transduction pathways, such as the mitogen-activated protein kinase …
[HTML][HTML] The p38 MAPK stress pathway as a tumor suppressor or more?
M Loesch, G Chen - Frontiers in bioscience: a journal and virtual …, 2008 - ncbi.nlm.nih.gov
Abstract p38 mitogen-activated protein kinases (p38 MAPKs) are a group of serine/threonine
protein kinases that together with ERK (extracellular signal-regulated kinases) and JNK (c …
protein kinases that together with ERK (extracellular signal-regulated kinases) and JNK (c …
p38 MAP kinase inhibitors: many are made, but few are chosen.
C Dominguez, DA Powers, N Tamayo - Current opinion in drug …, 2005 - europepmc.org
The mitogen-activated protein kinase (MAPK) p38 is a Ser/Thr kinase, originally isolated
from lipopolysaccharide-stimulated monocytes. There are four isoforms of the enzyme …
from lipopolysaccharide-stimulated monocytes. There are four isoforms of the enzyme …
Mammalian MAPK signal transduction pathways activated by stress and inflammation: a 10-year update
JM Kyriakis, J Avruch - Physiological reviews, 2012 - journals.physiology.org
The mammalian stress-activated families of mitogen-activated protein kinases (MAPKs)
were first elucidated in 1994, and by 2001, substantial progress had been made in …
were first elucidated in 1994, and by 2001, substantial progress had been made in …
Molecular cloning of human p38 MAP kinase
J Han, B Richter, Z Li, VV Kravchenko… - Biochimica et Biophysica …, 1995 - Elsevier
Mitogen-activated protein (MAP) kinases are intracellular serine/threonine kinases activated
by dual phosphorylation of adjacent threonine (T) and tyrosine (Y). A diverse number of …
by dual phosphorylation of adjacent threonine (T) and tyrosine (Y). A diverse number of …
Generation and characterization of p38β (MAPK11) gene-targeted mice
VA Beardmore, HJ Hinton, C Eftychi… - … and cellular biology, 2005 - Taylor & Francis
p38 mitogen-activated protein kinases (MAPKs) are activated primarily in response to
inflammatory cytokines and cellular stress, and inhibitors which target the p38α and p38β …
inflammatory cytokines and cellular stress, and inhibitors which target the p38α and p38β …