Mitogen-activated protein (MAP) kinase cascades represent one of the major signal systems
used by eukaryotic cells to transduce extracellular signals into cellular responses. Four MAP …

The p38 mitogen-activated protein kinase (MAPK) group is represented by four isoforms in
mammals (p38α, p38β2, p38γ and p38δ). These p38 MAPK isoforms appear to mediate …

p38 is a proline-directed serine/threonine kinase that is activated by inflammatory cytokines
and cellular stress. At present, four isoforms of p38 have been identified and termed α, β, γ …

MAP kinases are signaling intermediaries that allow eukaryotic cells to interpret and
respond to many different stimuli. Three major MAP kinase pathways have been identified …

The mitogen-activated protein kinase (MAPK) superfamily consists of three main protein
kinase families: the extracellular signal-regulated protein kinases (ERKs), the c-Jun N …

The p38 signalling transduction pathway, a Mitogen-activated protein (MAP) kinase
pathway, plays an essential role in regulating many cellular processes including …

Part of the cellular response to toxins, physical stresses and inflammatory cytokines occurs
by signalling via the stress-activated protein kinase (SAPK) and p38 reactivating kinase …

Publisher Summary This chapter discusses that the network of immune and inflammatory
responses is comprised of a variety of cell types. Coordination of this network occurs through …

All four members of the mammalian p38 mitogen-activated protein kinase (MAPK) family
(p38α, p38β, p38γ and p38δ) are activated by dual phosphorylation in the TGY motif in the …

Mitogen-activated protein (MAP) kinases are involved in many cellular processes. Here we
describe the cloning and characterization of a new MAP kinase, p38-2. p38-2 belongs to the …