Background Invasive aspergillosis (IA) is the most common cause of death associated with
fungal infection in the developed world. Historically, susceptibility to IA has been associated …

Heterogeneity among Aspergillus fumigatus isolates results in unique virulence potential
and inflammatory responses. How these isolates drive specific immune responses and how …

Incidences of invasive pulmonary aspergillosis, an infection caused predominantly by
Aspergillus fumigatus, have increased due to the growing number of immunocompromised …

Invasive aspergillosis (IA) is one of the most difficult to treat and, consequently, one of the
most lethal fungal infections known to man. Continued use of immunosuppressive agents …

The human lung is constantly exposed to Aspergillus fumigatus spores, the most prevalent
worldwide cause of fungal respiratory disease. Pulmonary tissue damage is a unifying …

Invasive aspergillosis (IA) remains a devastating disease in immune compromised patients
despite significant advances in our understanding of fungal virulence and host defense …

The sequential pathogenesis of pulmonary aspergillosis was studied and the role of
inflammatory cytokines in host response to Aspergillus fumigatus was characterized in …

Aspergillus fumigatus, a ubiquitous airborne fungus, can cause invasive infection in
immunocompromised individuals but also triggers allergic bronchopulmonary aspergillosis …

Humans are continuously exposed to airborne spores of the saprophytic fungus Aspergillus
fumigatus. However, in healthy individuals pulmonary host defense mechanisms efficiently …

Previous work has shown that environmental and clinical isolates of Aspergillus fumigatus
represent a diverse population that occupies a variety of niches, has extensive genetic …