The main aim of this work was to develop novel targeted sterically stabilised pH-sensitive
liposomes tailored to promote efficient intracellular delivery of therapeutic molecules into …

In the first part, medical applications of liposomes loaded with small molecular weight drugs
is discussed and the use of sterically stabilized liposomes containing doxorubicin in cancer …

In many applications, an ability of liposomes to retain drug and then rapidly release it at
some later time would be of benefit. In this work, we investigate the ability of cationic large …

Abstract pH-sensitive liposomes are interesting carriers for drug-delivery, undertaking rapid
bilayer destabilization in response to pH changes, allied to tumor accumulation, a desirable …

Since their description 30 years ago 1, liposomes (phospholipid bilayer vesicles) have found
widespread use as model membrane systems, and have been extensively investigated for …

pH-triggered lipid-membranes designed from biophysical principles are evaluated in the
form of targeted liposomal doxorubicin with the aim to ultimately better control the growth of …

A growing amount of literature describes the development and applications of novel
targeting and/or release triggering schemes to improve the therapeutic index of drugs …

Targeted liposomal drug formulations may enter cells by receptor-mediated endocytosis and
then traffick by membrane flow into acidic intracellular compartments. In order to understand …

Purpose To develop a liposomal system with high drug loading (DL) for intravenous (iv)
delivery of a poorly water-soluble basic drug, asulacrine (ASL). Methods A thin-film …

Liposomes have been extensively used as effective nanocarriers, providing better solubility,
higher stability and slower release of drugs compared to free drug administration. They are …