Isoquinoline alkaloids are a kind of small molecular compounds with isoquinoline structure
which widely exist in natural plants. A large number of studies have confirmed that these …

Isoquinoline alkaloids are an important class of natural products that are abundant in the
plant kingdom and exhibit a wide range of structural diversity and biological activities. With …

In the last years, traditional natural products have been the center of attention for the
scientific community and exploration of their therapeutic abilities is proceeding permanently …

Background & Objective: The emergence of multidrug-resistant virus, bacteria and fungi has
created an urgent need for the development of novel antibiotic drugs from natural products …

The present review describes research on novel natural isoquinoline alkaloids and their N-
oxides isolated from different plant species. More than 200 biological active compounds …

The wide variety of potent biological activities of natural and synthetic isoquinoline alkaloids
encouraged us to develop novel antimicrobial isoquinoline compounds. We synthesized a …

Viruses are widely recognized as the primary cause of infectious diseases around the world.
The ongoing global pandemic due to the emergence of SARS-CoV-2 further added fuel to …

Background: The quinoline moiety has been reported to be a privileged structure due to its
presence in many drugs. It appears in alkaloids and natural products such as quinine …

Isoquinoline alkaloids, an important class of N‐based heterocyclic compounds, have
attracted considerable attention from researchers worldwide since the early 19th century …

Benzyl tetrahydroisoquinoline alkaloids have interesting biological activity. This work aims at
investigating Grignard conditions for the preparation of models of 1-(substitutedbenzyl)-1, 2 …