Osteoarthritis (OA) is a joint pathology characterized by progressive cartilage degradation.
Medical care is mainly based on alleviating pain symptoms. Compelling studies report the …

Apoptosis is a highly-regulated, active process of cell death involved in development,
homeostasis and aging. Dysregulation of apoptosis leads to pathological states, such as …

Cell death with morphological and molecular features of apoptosis has been detected in
osteoarthritic (OA) cartilage, which suggests a key role for chondrocyte death/survival in the …

Objective To determine which kind of cell death occurs in cartilage from patients with
osteoarthritis (OA). Methods Seven normal and 16 OA cartilage samples were collected at …

Osteoarthritis (OA) is a degenerative joint disease characterized by articular cartilage
degradation and changes in the subchondral bone. Over the last two decades, there has …

Osteoarthritis (OA) is the most common chronic joint disease in the elderly population,
causing significant pain and disability. Because the cardinal feature of OA is a progressive …

Osteoarthritis is a common disease and is frequently encountered in the older population;
the incidence rises sharply with age. It is estimated that more than 360 million people suffer …

The death of chondrocytes and the loss of extracellular matrix are the central features in
cartilage degeneration during Osteoarthritis (OA) pathogenesis. The mechanism by which …

Articular cartilage is a highly specialized and uniquely structured biomaterial that forms the
smooth, gliding surface of the diarthrodial joints. It consists of an extracellular matrix that is …

Objective Chondrocyte apoptosis has been described in both human and experimentally
induced osteoarthritis (OA), but its importance in the etiopathogenesis of OA is uncertain …