The role of autophagy in osteoarthritis
R Duan, H Xie, ZZ Liu - Frontiers in cell and developmental biology, 2020 - frontiersin.org
Chondrocytes are the only cell type in normal cartilage. The pathological changes of
osteoarthritis (OA) mostly revolve around the apoptosis and dysfunction of chondrocytes …
osteoarthritis (OA) mostly revolve around the apoptosis and dysfunction of chondrocytes …
Characterization of apoptosis in articular cartilage derived from the knee joints of patients with osteoarthritis
G Musumeci, C Loreto, ML Carnazza… - Knee Surgery, Sports …, 2011 - Springer
Purpose The present study was conduced in order to analyse the molecular changes during
the apoptotic cascade in knee articular cartilage of patients with OA. Method Articular …
the apoptotic cascade in knee articular cartilage of patients with OA. Method Articular …
Mechanisms of chondrocyte apoptosis
M Lotz, S Hashimoto, K Kühn - Osteoarthritis and Cartilage, 1999 - Elsevier
This study addresses the occurrence and significance of chondrocyte apoptosis in the
pathogenesis of cartilage destruction. Chondrocyte apoptosis can be inducedin vitroby nitric …
pathogenesis of cartilage destruction. Chondrocyte apoptosis can be inducedin vitroby nitric …
Pathomechanisms of posttraumatic osteoarthritis: chondrocyte behavior and fate in a precarious environment
J Riegger, RE Brenner - International journal of molecular sciences, 2020 - mdpi.com
Traumatic injuries of the knee joint result in a wide variety of pathomechanisms, which
contribute to the development of so-called posttraumatic osteoarthritis (PTOA). These …
contribute to the development of so-called posttraumatic osteoarthritis (PTOA). These …
Noncanonical Pyroptosis Triggered by Macrophage‐Derived Extracellular Vesicles in Chondrocytes Leading to Cartilage Catabolism in Osteoarthritis
T Ebata, MA Terkawi, K Kitahara… - Arthritis & …, 2023 - Wiley Online Library
Objective The severity of osteoarthritis (OA) and cartilage degeneration is highly correlated
with the development of synovitis, which is mediated by the activity of inflammatory …
with the development of synovitis, which is mediated by the activity of inflammatory …
[PDF][PDF] OA cartilage derived chondrocytes encapsulated in poly (ethylene glycol) diacrylate (PEGDA) for the evaluation of cartilage restoration and apoptosis in an in …
G Musumeci, C Loreto, ML Carnazza, I Strehin… - … and histopathology, Vol …, 2011 - hh.um.es
Osteoarthritis (OA) is characterized by cartilage attrition, subchondral bone remodeling,
osteophyte formation and synovial inflammation. Perturbed homeostasis caused by …
osteophyte formation and synovial inflammation. Perturbed homeostasis caused by …
Current understanding of osteoarthritis pathogenesis and relevant new approaches
Osteoarthritis (OA) is the most common degenerative joint disease that causes painful
swelling and permanent damage to the joints in the body. The molecular mechanisms of OA …
swelling and permanent damage to the joints in the body. The molecular mechanisms of OA …
[HTML][HTML] Chondrocyte death by apoptosis is associated with cartilage matrix degradation
CM Thomas, CJ Fuller, CE Whittles, M Sharif - Osteoarthritis and Cartilage, 2007 - Elsevier
OBJECTIVES: To investigate the frequency of chondrocyte apoptosis in equine articular
cartilage (AC) specimens and to examine the relationship between the process of cell death …
cartilage (AC) specimens and to examine the relationship between the process of cell death …
Targeting cell death: pyroptosis, ferroptosis, apoptosis and necroptosis in osteoarthritis
J Yang, S Hu, Y Bian, J Yao, D Wang, X Liu… - Frontiers in cell and …, 2022 - frontiersin.org
New research has shown that the development of osteoarthritis (OA) is regulated by different
mechanisms of cell death and types of cytokines. Therefore, elucidating the mechanism of …
mechanisms of cell death and types of cytokines. Therefore, elucidating the mechanism of …
PI3K/Akt and caspase pathways mediate oxidative stress-induced chondrocyte apoptosis
D Li, S Ni, KS Miao, C Zhuang - Cell Stress and Chaperones, 2019 - Springer
Chondrocyte apoptosis is closely related to the development and progression of
osteoarthritis (OA); however, the underlying mechanisms remain enigmatic. Previous studies …
osteoarthritis (OA); however, the underlying mechanisms remain enigmatic. Previous studies …