Recent investigations into the striking heterogeneity of cellular reaction patterns that are
characteristic for, and puzzling in, osteoarthritic cartilage degeneration addressed apoptotic …

Ageing processes play a major contributing role for the development of Osteoarthritis (OA).
This prototypic degenerative condition of ageing is the most common form of arthritis and is …

The extracellular matrix of articular cartilage is the primary target of osteoarthritic cartilage
degradation. However, cartilage cells have a pivotal role during osteoarthritis, as they are …

Arthritis is inflammation of the joints accompanied by osteochondral destruction. It can take
many forms, including osteoarthritis, rheumatoid arthritis, and psoriatic arthritis. These …

Osteoarthritis (OA) is one of the most common diseases leading to physical disability, with
age being the main risk factor, and degeneration of articular cartilage is the main focus for …

Aging is a natural process characterized by the declining ability of the different organs and
tissues to respond to stress, increasing homeostatic imbalance and risk of disease …

OBJECTIVE: This study addresses the effects of tumor necrosis factor-α (TNF-α) and
interleukin-1β (IL-1β) on cell death in human chondrocytes. METHODS: Osteoarthritis (OA) …

Objective Autophagy, an evolutionarily conserved process for the bulk degradation of
cytoplasmic components, serves as a cell survival mechanism. The purpose of this study …

Osteoarthritis (OA) is the most prevalent joint disease characterized by pain and
degenerative lesions of the cartilage, subchondral bone, and other joint tissues. The causes …

Aging is a natural process by which every single living organism approaches its twilight of
existence in a natural way. However, aging is also linked to the pathogenesis of a number of …