Osteoarthritis (OA) is a progressive and disabling disease resulting from a combination of
risk factors, including advancing age, genetics, trauma, knee malalignment, increased …

Purpose Recent scientific reports have revealed a close association between ferroptosis
and the occurrence and development of osteoarthritis (OA). Nevertheless, the precise …

Objective Osteoarthritis (OA) exposes all joint tissues to physiologic stresses, increasing the
need to clear apoptotic cells from tissues, including the synovium. We undertook this study to …

Osteoarthritis (OA) is a chronic disease and the most common orthopedic disorder. A vast
majority of the social OA burden is related to hips and knees. The prevalence of knee OA …

Osteoarthritis is characterized by progressive breakdown of articular cartilage. This review
summarizes findings of the last year, which shed new light on mechanisms and factors …

Summary This Year in Review highlights a selection of articles published between the 2017
and 2018 Osteoarthritis Research Society International (OARSI) World Congress meetings …

Objective Chondrocyte apoptosis plays an important role in cartilage degeneration in
osteoarthritis (OA), and mechanical injury to cartilage induces chondrocyte apoptosis. In …

Objective When endoplasmic reticulum (ER) stress, ie, the excessive accumulation of
unfolded proteins in ER, endangers homeostasis, apoptosis is induced by C/EBP …

Osteoarthritis (OA), the most common form of degenerative joint disease, is linked to high
morbidity. It is predicted to be the single greatest cause of disability in the general population …

Introduction Synovial fibroblasts from rheumatoid arthritis show resistance to apoptotic
stimuli, indicating they may be difficult to treat. To clearly understand these mechanisms of …