The hypothalamus integrates endogenous and exogenous inputs to control the pituitary–
gonadal axis. The ultimate hypothalamic influence on reproductive activity is mediated …

Procreation is essential for survival of species. Not surprisingly, complex neuronal networks
have evolved to mediate the diverse internal and external environmental inputs that regulate …

Hypothalamic kisspeptin (Kiss1) neurons provide indispensable excitatory transmission to
gonadotropin-releasing hormone (GnRH) neurons for the coordinated release of …

Reproduction is associated with the circadian system, primarily as a result of the connectivity
between the biological clock in the suprachiasmatic nucleus (SCN) and reproduction …

The KiSS-1 gene encodes the peptide hormone kisspeptin, which acts as a principal
positive regulator of the reproductive axis by directly stimulating GnRH neuron activity. To …

Seasonal mammals use the photoperiodic variation in the nocturnal production of the pineal
hormone melatonin to synchronize their reproductive activity with seasons. In rodents, the …

Neurons that produce gonadotropin-releasing hormone (GnRH) reside in the basal
forebrain and drive reproductive function in mammals. Understanding the circuitry that …

Neurons that produce gonadotropin-releasing hormone (GnRH) drive the reproductive axis,
but the molecular and cellular mechanisms by which hormonal and environmental signals …

Many aspects of female reproduction often require intricate timing, ranging from the temporal
regulation of reproductive hormone secretion to the precise timing of sexual behaviour. In …

The neuropeptides kisspeptin (encoded by Kiss1) and RF amide‐related peptide‐3 (also
known as Gn IH; encoded by Rfrp) are potent stimulators and inhibitors, respectively, of …