Reduced expression of ferroportin1 and ceruloplasmin predicts poor prognosis in adrenocortical carcinoma

B Zhu, Q Zhi, Q Xie, X Wu, Y Gao, X Chen… - Journal of Trace Elements …, 2019 - Elsevier
Introduction Iron metabolism is tightly controlled in human cells. Dysregulation of iron
metabolism-related genes has been characterized as a promising prognostic biomarker in …

Pan‐cancer analysis of iron metabolic landscape across the Cancer Genome Atlas

S Zhang, W Chang, H Wu, YH Wang… - Journal of Cellular …, 2020 - Wiley Online Library
Iron is an essential metal ion in the human body and usually dysregulated in cancers.
However, a comprehensive overview of the iron‐related genes and their clinical relevance …

[HTML][HTML] Identification and quantification of iron metabolism landscape on therapy and prognosis in bladder cancer

X Song, S Xin, Y Zhang, J Mao, C Duan… - Frontiers in Cell and …, 2022 - frontiersin.org
The morbidity of bladder cancer (BLCA) is high and has gradually elevated in recent years.
BLCA is also characterized by high recurrence and high invasiveness. Due to the drug …

Development of a gene signature associated with iron metabolism in lung adenocarcinoma

J Qin, Z Xu, K Deng, F Qin, J Wei, L Yuan, Y Sun… - …, 2021 - Taylor & Francis
There are few studies on the role of iron metabolism genes in predicting the prognosis of
lung adenocarcinoma (LUAD). Therefore, our research aims to screen key genes and to …

[HTML][HTML] The landscape of iron metabolism-related and methylated genes in the prognosis prediction of clear cell renal cell carcinoma

Y Mou, Y Zhang, J Wu, B Hu, C Zhang, C Duan… - Frontiers in …, 2020 - frontiersin.org
Background: Clear cell renal cell carcinoma (ccRCC) is characteristics of resistance to
chemotherapy and radiotherapy. The prognosis of ccRCC was dismay with immense …

[HTML][HTML] Decreased expression of ferroportin in prostate cancer Corrigendum in/10.3892/ol. 2021.12518

D Xue, CX Zhou, YB Shi, H Lu… - Oncology letters, 2015 - spandidos-publications.com
The present study examined the expression levels of ferroportin, a transmembrane protein
that transports iron from the inside of a cell to the outside, in the prostate cancer PC3, DU145 …

[HTML][HTML] Identification of iron metabolism-related genes as prognostic indicators for papillary thyroid carcinoma: a retrospective study

T Jin, L Ge, J Chen, W Wang, L Zhang, M Ge - PeerJ, 2023 - peerj.com
Background The thyroid cancer subtype that occurs more frequently is papillary thyroid
carcinoma (PTC). Despite a good surgical outcome, treatment with traditional antitumor …

[HTML][HTML] Novel characterization discoveries of ferroptosis-associated molecules in COAD microenvironment based TCGA data

S Baldi, Y He, I Ivanov, Y Sun, W Feng… - Frontiers in Molecular …, 2022 - frontiersin.org
Background and Objective: One of the most recent forms of programmed cell death,
ferroptosis, is crucial in tumorigenesis. Ferroptosis is characterized by iron-dependent …

[HTML][HTML] Identification and analysis of a prognostic ferroptosis and iron-metabolism signature for esophageal squamous cell carcinoma

M Zhao, M Li, Y Zheng, Z Hu, J Liang, G Bi… - Journal of …, 2022 - ncbi.nlm.nih.gov
Methods: The association of iron metabolism and ferroptosis-related genes with the
prognosis, copy number variation (CNV), TMB, and immune cell infiltration of ESCC was …

Prospective role and immunotherapeutic targets of sideroflexin protein family in lung adenocarcinoma: evidence from bioinformatics validation

HH Dang, HDK Ta, TTT Nguyen, G Anuraga… - Functional & Integrative …, 2022 - Springer
As lung cancer remains the leading cause of cancer deaths globally, characterizing the
tumor molecular profiles is crucial to tailoring treatments for individuals at advanced stages …