Background In a multisite clinical research collaboration, institutions may or may not use the
same common data model (CDM) to store clinical data. To overcome this challenge, we …

Background: The standard Fast Healthcare Interoperability Resources (FHIR) is widely used
in health information technology. However, its use as a standard for health research is still …

Background: The harmonization and standardization of digital medical information for
research purposes is a challenging and ongoing collaborative effort. Current research data …

Background: With the advent of the digital economy and the aging population, the demand
for diversified health care services and innovative care delivery models has been …

Background Increasing digitalization in the medical domain gives rise to large amounts of
health care data, which has the potential to expand clinical knowledge and transform patient …

Background Machine learning–enabled clinical information systems (ML-CISs) have the
potential to drive health care delivery and research. The Fast Healthcare Interoperability …

Background Information technology has shifted paper-based documentation in the health
care sector into a digital form, in which patient information is transferred electronically from …

Background Real-world data (RWD) and real-world evidence (RWE) are playing
increasingly important roles in clinical research and health care decision-making. To …

Background: Clinical trial registries increase transparency in medical research by making
information and results of planned, ongoing, and completed studies publicly available …

Background: An essential step in any medical research project after identifying the research
question is to determine if there are sufficient patients available for a study and where to find …