Background: Molecular characterisation of single circulating tumour cells (CTCs) holds
considerable promise for predictive biomarker assessment and to explore CTC …

Introduction Genes that are expressed in a highly tissue-or disease-specific manner provide
possible targets for therapeutics, early detection of cancer, and monitoring of disease …

Numerous single‐institutional studies and a large pooled analysis have demonstrated that
the presence of disseminated tumor cells (DTCs) in the bone marrow (BM) from patients with …

The development and use of molecular-based therapy for breast cancer and other human
malignancies will require a detailed molecular genetic analysis of patient tissues. The recent …

Detection of tumor cells in blood and bone marrow is increasingly used for the staging of
patients with breast cancer and to evaluate the presence of tumor cells in peripheral blood …

Cell lines derived from human tumors have historically served as the primary experimental
model system for exploration of tumor cell biology and pharmacology. Cell line studies …

With the objective of discovering novel putative intervention sites for anticancer therapy, we
compared transcriptional profiles of breast cancer, lung squamous cell cancer (LSCC), lung …

Purpose: We examined the feasibility of using molecular characterization of circulating tumor
cells as a method for early detection of breast cancer. Research Design: Women without a …

Proteins are used as prognostic and predictive biomarkers in breast cancer. However, the
variability of protein expression within the same tumor is not well studied. The aim of this …

Background In this study we have validated the feasibility of detecting disseminated tumor
cells (DTC) by real-time reverse-transcriptase polymerase chain reaction (RT-PCR) …