Semiautomated isolation and molecular characterisation of single or highly purified tumour cells from CellSearch enriched blood samples using dielectrophoretic cell …
DJE Peeters, B De Laere, GG Van den Eynden… - British journal of …, 2013 - nature.com
Background: Molecular characterisation of single circulating tumour cells (CTCs) holds
considerable promise for predictive biomarker assessment and to explore CTC …
considerable promise for predictive biomarker assessment and to explore CTC …
Evaluation of expression based markers for the detection of breast cancer cells
NM Brown, TT Stenzel, PN Friedman, J Henslee… - Breast cancer research …, 2006 - Springer
Introduction Genes that are expressed in a highly tissue-or disease-specific manner provide
possible targets for therapeutics, early detection of cancer, and monitoring of disease …
possible targets for therapeutics, early detection of cancer, and monitoring of disease …
A concept for the standardized detection of disseminated tumor cells in bone marrow from patients with primary breast cancer and its clinical implementation
T Fehm, S Braun, V Muller, W Janni… - … Journal of the …, 2006 - Wiley Online Library
Numerous single‐institutional studies and a large pooled analysis have demonstrated that
the presence of disseminated tumor cells (DTCs) in the bone marrow (BM) from patients with …
the presence of disseminated tumor cells (DTCs) in the bone marrow (BM) from patients with …
In Vivo Gene Expression Profile Analysis of Human Breast Cancer Progression
DC Sgroi, S Teng, G Robinson, R LeVangie… - Cancer research, 1999 - AACR
The development and use of molecular-based therapy for breast cancer and other human
malignancies will require a detailed molecular genetic analysis of patient tissues. The recent …
malignancies will require a detailed molecular genetic analysis of patient tissues. The recent …
Comparison of immunocytochemistry, reverse transcriptase polymerase chain reaction, and nucleic acid sequence–based amplification for the detection of circulating …
AC Lambrechts, AJ Bosma, SG Klaver, B Top… - Breast cancer research …, 1999 - Springer
Detection of tumor cells in blood and bone marrow is increasingly used for the staging of
patients with breast cancer and to evaluate the presence of tumor cells in peripheral blood …
patients with breast cancer and to evaluate the presence of tumor cells in peripheral blood …
A comparison of gene expression signatures from breast tumors and breast tissue derived cell lines
DT Ross, CM Perou - Disease markers, 2001 - content.iospress.com
Cell lines derived from human tumors have historically served as the primary experimental
model system for exploration of tumor cell biology and pharmacology. Cell line studies …
model system for exploration of tumor cell biology and pharmacology. Cell line studies …
Tissue-wide expression profiling using cDNA subtraction and microarrays to identify tumor-specific genes
S Amatschek, U Koenig, H Auer, P Steinlein, M Pacher… - Cancer research, 2004 - AACR
With the objective of discovering novel putative intervention sites for anticancer therapy, we
compared transcriptional profiles of breast cancer, lung squamous cell cancer (LSCC), lung …
compared transcriptional profiles of breast cancer, lung squamous cell cancer (LSCC), lung …
Evaluation of a panel of tumor markers for molecular detection of circulating cancer cells in women with suspected breast cancer
MM Reinholz, A Nibbe, LM Jonart, K Kitzmann… - Clinical Cancer …, 2005 - AACR
Purpose: We examined the feasibility of using molecular characterization of circulating tumor
cells as a method for early detection of breast cancer. Research Design: Women without a …
cells as a method for early detection of breast cancer. Research Design: Women without a …
Common protein biomarkers assessed by reverse phase protein arrays show considerable intratumoral heterogeneity in breast cancer tissues
K Malinowsky, M Raychaudhuri, T Buchner, S Thulke… - PLoS …, 2012 - journals.plos.org
Proteins are used as prognostic and predictive biomarkers in breast cancer. However, the
variability of protein expression within the same tumor is not well studied. The aim of this …
variability of protein expression within the same tumor is not well studied. The aim of this …
Prognostic significance of disseminated tumor cells as detected by quantitative real-time reverse-transcriptase polymerase chain reaction in patients with breast …
Background In this study we have validated the feasibility of detecting disseminated tumor
cells (DTC) by real-time reverse-transcriptase polymerase chain reaction (RT-PCR) …
cells (DTC) by real-time reverse-transcriptase polymerase chain reaction (RT-PCR) …