Autoimmune diseases, with the exception of rheumatoid arthritis and autoimmune thyroiditis,
are individually rare, but together they affect approximately 5 percent of the population in …

There have been significant advances in our understanding of human autoimmunity that
have led to improvements in classification and diagnosis and, most importantly, research …

Autoimmune disease: why and where it occurs | Nature Medicine Skip to main content Thank
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Biological systems can be analyzed in terms of effector mechanisms and factors responsible
for their control. Autoimmunity can be viewed as a two-stage process in which a breakdown …

In this Overview, common themes of the accompanying News & Views on RA, SLE, IDDM,
thyroiditis and MS are discussed. A unifying concept for the development of these and other …

The fact that autoimmune diseases share subphenotypes, physiopathological mechanisms
and genetic factors has been called autoimmune tautology, and indicates that they have a …

An increasing number of individuals throughout the world are affected by autoimmune
disease, a large and diverse group of disorders that are categorized by tissue injury or …

Although deletion mechanisms may be responsible for much of the non-reactivity to self,
immune manipulations [1, 2], which result in the development of autoimmune diseases, have …

Monogenic autoimmune syndromes provide a rare yet powerful glimpse into the
fundamental mechanisms of immunologic tolerance. Such syndromes reveal not only the …

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