Regulation of contraction in striated muscle
AM Gordon, E Homsher, M Regnier - Physiological reviews, 2000 - journals.physiology.org
Ca2+ regulation of contraction in vertebrate striated muscle is exerted primarily through
effects on the thin filament, which regulate strong cross-bridge binding to actin. Structural …
effects on the thin filament, which regulate strong cross-bridge binding to actin. Structural …
A new look at thin filament regulation in vertebrate skeletal muscle
It is 30 years since Ebashi and colleagues showed that Ca2+ ions directly affect regulation
of the myosin‐actin interaction in muscle through the action of tropomyosin and troponin on …
of the myosin‐actin interaction in muscle through the action of tropomyosin and troponin on …
An atomic model of the thin filament in the relaxed and Ca2+-activated states
A Pirani, MV Vinogradova, PMG Curmi, WA King… - Journal of molecular …, 2006 - Elsevier
Contraction of striated muscles is regulated by tropomyosin strands that run continuously
along actin-containing thin filaments. Tropomyosin blocks myosin-binding sites on actin in …
along actin-containing thin filaments. Tropomyosin blocks myosin-binding sites on actin in …
Thin Filament Proteins and Thin Filament-Linked Regulation of Vertebrate Muscle Contractio
PC Leavis, J Gergely… - Critical Reviews in …, 1984 - Taylor & Francis
This review deals with the regulatory system of striated muscle. In current parlance, the term
regulatory system refers to those proteins that are located in the so-called thin filaments of …
regulatory system refers to those proteins that are located in the so-called thin filaments of …
[引用][C] Structural aspects of troponin-tropomyosin regulation of skeletal muscle contraction
AS Zot, JD Potter - Annual review of biophysics and biophysical …, 1987 - annualreviews.org
REGULATION BY TROPONIN-TROPOMYOSIN 537 structural changes cause increased
interaction between actin and myosin, enhanced actomyosin ATPase activity, and …
interaction between actin and myosin, enhanced actomyosin ATPase activity, and …
Tropomyosin and the steric mechanism of muscle regulation
Contraction in all muscles must be precisely regulated and requisite control systems must be
able to adjust to changes in physiological and myopathic stimuli. In this chapter, we outline …
able to adjust to changes in physiological and myopathic stimuli. In this chapter, we outline …
In Vitro Motility Analysis of Actin-Tropomyosin Regulation by Troponin and Calcium: THE THIN FILAMENT IS SWITCHED AS A SINGLE COOPERATIVE UNIT (∗)
IDC Fraser, SB Marston - Journal of Biological Chemistry, 1995 - ASBMB
In striated muscles, contractility is controlled by Ca 2+ binding to the regulatory protein
complex troponin, which is a component of the thin filaments. Troponin is an allosteric …
complex troponin, which is a component of the thin filaments. Troponin is an allosteric …
Thin filament near‐neighbour regulatory unit interactions affect rabbit skeletal muscle steady‐state force‐Ca2+ relations
M Regnier, AJ Rivera, CK Wang… - The Journal of …, 2002 - Wiley Online Library
The role of cooperative interactions between individual structural regulatory units (SUs) of
thin filaments (7 actin monomers: 1 tropomyosin: 1 troponin complex) on steady‐state Ca2+ …
thin filaments (7 actin monomers: 1 tropomyosin: 1 troponin complex) on steady‐state Ca2+ …
Skeletal and cardiac muscle contractile activation: tropomyosin “rocks and rolls”
AM Gordon, M Regnier, E Homsher - Physiology, 2001 - journals.physiology.org
Changes in thin filament structure induced by Ca2+ binding to troponin and subsequent
strong cross-bridge binding regulate additional strong cross-bridge attachment, force …
strong cross-bridge binding regulate additional strong cross-bridge attachment, force …
A Direct Regulatory Role for Troponin T and a Dual Role for Troponin C in the Ca2+ Regulation of Muscle Contraction (∗)
JD Potter, Z Sheng, BS Pan, J Zhao - Journal of Biological Chemistry, 1995 - ASBMB
Troponin (Tn), containing three subunits: Ca 2+ binding (TnC), inhibitory (TnI), and
tropomyosin binding (TnT), plays a crucial role in the Ca 2+ regulation of vertebrate striated …
tropomyosin binding (TnT), plays a crucial role in the Ca 2+ regulation of vertebrate striated …