Natural rewards, such as food and social interaction, as well as drugs of abuse elicit
increased mesolimbic dopamine release in the nucleus accumbens (NAc). Drugs of abuse …

Objective To test whether high‐fat diet (HFD) decreases dopaminergic tone in reward
regions of the brain and evaluate whether these changes reverse after removal of the HFD …

The development of diet-induced obesity (DIO) can potently alter multiple aspects of
dopamine signaling, including dopamine transporter (DAT) expression and dopamine …

Increased caloric intake in dietary obesity could be driven by central mechanisms that
regulate reward-seeking behavior. The mesolimbic dopamine system, and the nucleus …

Dopamine influences food intake behavior. Reciprocally, food intake, especially of palatable
dietary items, can modulate dopamine-related brain circuitries. Among these reciprocal …

High-fat diets are linked with obesity and changes in dopamine neurotransmission.
Mounting evidence shows that saturated fat impacts dopamine neurons and their terminal …

In rats reduced to 80% of normal body weight (n= 9), the basal levels of extracellular
dopamine (DA) in the nucleus accumbens (NAC), as determined by microdialysis …

Recent studies indicate that decreased central dopamine is associated with diet-induced
obesity in humans and in animal models. In the current study, the authors assessed the …

Weight loss is known to alter food intake and drug self-administration, but the neural basis of
this is unknown. Therefore, we studied effects of weight loss on neurochemistry of a brain …

Feeding is associated with increases in the activity of the mesolimbic dopamine (DA) system
which originates in the ventral tegmental area (VTA) and projects heavily to the nucleus …