Development and regulation of exosome‐based therapy products
EV Batrakova, MS Kim - Wiley Interdisciplinary Reviews …, 2016 - Wiley Online Library
Recently, various innovative therapies involving the ex vivo manipulation and subsequent
reintroduction of exosome‐based therapeutics into humans have been developed and …
reintroduction of exosome‐based therapeutics into humans have been developed and …
[HTML][HTML] Encapsulation and assessment of therapeutic cargo in engineered exosomes: a systematic review
Z Chen, M Xiong, J Tian, D Song, S Duan… - Journal of …, 2024 - Springer
Exosomes are nanoscale extracellular vesicles secreted by cells and enclosed by a lipid
bilayer membrane containing various biologically active cargoes such as proteins, lipids …
bilayer membrane containing various biologically active cargoes such as proteins, lipids …
[HTML][HTML] Unlocking the power of exosomes for crossing biological barriers in drug delivery
RO Elliott, M He - Pharmaceutics, 2021 - mdpi.com
Since the 2013 Nobel Prize was awarded for the discovery of vesicle trafficking, a subgroup
of nanovesicles called exosomes has been driving the research field to a new regime for …
of nanovesicles called exosomes has been driving the research field to a new regime for …
Exosomes as a next-generation drug delivery system: An update on drug loading approaches, characterization, and clinical application challenges
Exosomes are small nanoparticles secreted by almost all cells and have a well-known role
in intercellular communication. They are found in different body fluids and can also be …
in intercellular communication. They are found in different body fluids and can also be …
Exosomes: Large-scale production, isolation, drug loading efficiency, and biodistribution and uptake
I Kimiz-Gebologlu, SS Oncel - Journal of Controlled Release, 2022 - Elsevier
Exosomes are nanovesicles with different contents that play a role in various biological and
pathological processes. It offers significant advantages over other delivery systems such as …
pathological processes. It offers significant advantages over other delivery systems such as …
Exosomes as a drug delivery system in cancer therapy: potential and challenges
G Kibria, EK Ramos, Y Wan, DR Gius… - Molecular …, 2018 - ACS Publications
Exosomes play a pivotal role in mediating intercellular communications and package
delivery. They have recently been discovered to serve as diagnostic biomarkers as well as a …
delivery. They have recently been discovered to serve as diagnostic biomarkers as well as a …
Research advances of engineered exosomes as drug delivery carrier
L Huang, E Wu, J Liao, Z Wei, J Wang, Z Chen - ACS omega, 2023 - ACS Publications
Exosomes are nanoscale vesicles secreted by living cells that have similar membrane
composition to parental cells and carry a variety of proteins, lipids, and nucleic acids …
composition to parental cells and carry a variety of proteins, lipids, and nucleic acids …
[HTML][HTML] Current strategies for exosome cargo loading and targeting delivery
Extracellular vesicles (EVs) such as ectosomes and exosomes have gained attention as
promising natural carriers for drug delivery. Exosomes, which range from 30 to 100 nm in …
promising natural carriers for drug delivery. Exosomes, which range from 30 to 100 nm in …
Exosomes as novel bio-carriers for gene and drug delivery
XC Jiang, JQ Gao - International journal of pharmaceutics, 2017 - Elsevier
Clinical treatments have stalled in certain diseases due to a lack of proper therapeutic
delivery systems. Recent studies have identified exosomes for their potential use as cell-free …
delivery systems. Recent studies have identified exosomes for their potential use as cell-free …
[HTML][HTML] Recent advances in exosome-based drug delivery for cancer therapy
Simple Summary Exosomes derived from various sources can deliver therapeutic agents
such as small molecule drugs, nucleic acids, and proteins to cancer cells by passive or …
such as small molecule drugs, nucleic acids, and proteins to cancer cells by passive or …