[HTML][HTML] Exosomes: biological pharmaceutical nanovectors for theranostics

SC Thomas, JW Kim, GM Pauletti… - … in bioengineering and …, 2022 - frontiersin.org
Exosomes are natural cell-derived nanovesicles of endocytic origin that enable cellular
crosstalk by transferring encapsulated molecular cargos across biological barriers, thereby …

A review on the use of extracellular vesicles for the delivery of drugs and biological therapeutics

SJ Amina, T Azam, F Dagher, B Guo - Expert Opinion on Drug …, 2024 - Taylor & Francis
Introduction Exosomes, a type of extracellular vesicles, are effective tools for delivering small-
molecule drugs and biological therapeutics into cells and tissues. Surface modifications with …

[HTML][HTML] Exosomes and exosome-inspired vesicles for targeted drug delivery

SG Antimisiaris, S Mourtas, A Marazioti - Pharmaceutics, 2018 - mdpi.com
The similarities between exosomes and liposomes, together with the high organotropism of
several types of exosomes, have recently prompted the development of engineered …

[HTML][HTML] Biomimetic exosomes: a new generation of drug delivery system

X Wang, X Zhao, Y Zhong, J Shen… - Frontiers in bioengineering …, 2022 - frontiersin.org
Most of the naked drugs, including small molecules, inorganic agents, and
biomacromolecule agents, cannot be used directly for disease treatment because of their …

Extracellular vesicles in pharmacology: Novel approaches in diagnostics and therapy

Z Quadri, A Elsherbini, E Bieberich - Pharmacological research, 2022 - Elsevier
Exosomes are nano-sized lipid vesicles that are produced by all eukaryotic cells, and they
typically range in size from 30 to 150 nm. Exosomes were discovered almost 40 years ago; …

Pharmacokinetics of exosomes—an important factor for elucidating the biological roles of exosomes and for the development of exosome-based therapeutics

M Morishita, Y Takahashi, M Nishikawa… - Journal of …, 2017 - Elsevier
Exosomes are small membrane vesicles containing lipids, proteins, and nucleic acids.
Recently, researchers have uncovered that exosomes are involved in various biological …

Exosomes as drug carriers for cancer therapy

JE Pullan, MI Confeld, JK Osborn, J Kim… - Molecular …, 2019 - ACS Publications
Exosomes, biological extracellular vesicles, have recently begun to find use in targeted drug
delivery in solid tumor research. Ranging from 30–120 nm in size, exosomes are secreted …

[HTML][HTML] Recent advancements in the loading and modification of therapeutic exosomes

M Xu, Q Yang, X Sun, Y Wang - Frontiers in Bioengineering and …, 2020 - frontiersin.org
Exosomes have a rapid development of bio-nanoparticles for drug delivery and confluent
advances in next-generation diagnostics, monitoring the progression of several diseases …

[HTML][HTML] The advances and challenges in utilizing exosomes for delivering cancer therapeutics

M Yang, SY Wu - Frontiers in pharmacology, 2018 - frontiersin.org
Nanotechnology plays an important role in advancing treatment and diagnosis of a variety of
human diseases. The use of nanocarriers often leads to better pharmacokinetic and safety …

Advances in exosome-based drug delivery and tumor targeting: from tissue distribution to intracellular fate

J Shao, J Zaro, Y Shen - International journal of nanomedicine, 2020 - Taylor & Francis
Exosomes or small extracellular vesicles are considered a new generation of bioinspired-
nanoscale drug delivery system (DDS). Endogenous exosomes function as signalosomes …