Single-cell mRNA quantification and differential analysis with Census
Single-cell gene expression studies promise to reveal rare cell types and cryptic states, but
the high variability of single-cell RNA-seq measurements frustrates efforts to assay …
the high variability of single-cell RNA-seq measurements frustrates efforts to assay …
Experimental design for single-cell RNA sequencing
J Baran-Gale, T Chandra… - Briefings in functional …, 2018 - academic.oup.com
Single-cell RNA sequencing (scRNA-seq) has opened new avenues for the characterization
of heterogeneity in a large variety of cellular systems. As this is a relatively new technique …
of heterogeneity in a large variety of cellular systems. As this is a relatively new technique …
Characterizing noise structure in single-cell RNA-seq distinguishes genuine from technical stochastic allelic expression
JK Kim, AA Kolodziejczyk, T Ilicic… - Nature …, 2015 - nature.com
Single-cell RNA-sequencing (scRNA-seq) facilitates identification of new cell types and
gene regulatory networks as well as dissection of the kinetics of gene expression and …
gene regulatory networks as well as dissection of the kinetics of gene expression and …
Defining transcribed regions using RNA-seq
Next-generation sequencing technologies are revolutionizing genomics research. It is now
possible to generate gigabase pairs of DNA sequence within a week without time …
possible to generate gigabase pairs of DNA sequence within a week without time …
A systematic evaluation of single cell RNA-seq analysis pipelines
The recent rapid spread of single cell RNA sequencing (scRNA-seq) methods has created a
large variety of experimental and computational pipelines for which best practices have not …
large variety of experimental and computational pipelines for which best practices have not …
MULTI-seq: sample multiplexing for single-cell RNA sequencing using lipid-tagged indices
Sample multiplexing facilitates scRNA-seq by reducing costs and identifying artifacts such
as cell doublets. However, universal and scalable sample barcoding strategies have not …
as cell doublets. However, universal and scalable sample barcoding strategies have not …
Technical variations in low-input RNA-seq methodologies
Recent advances in RNA-seq methodologies from limiting amounts of mRNA have
facilitated the characterization of rare cell-types in various biological systems. So far …
facilitated the characterization of rare cell-types in various biological systems. So far …
Single-cell analyses to tailor treatments
Single-cell analyses to tailor treatments | Science Translational Medicine news careers
commentary Journals Science Science brought to you byGoogle Indexer Log in science science …
commentary Journals Science Science brought to you byGoogle Indexer Log in science science …
TimeLapse-seq: adding a temporal dimension to RNA sequencing through nucleoside recoding
RNA sequencing (RNA-seq) offers a snapshot of cellular RNA populations, but not temporal
information about the sequenced RNA. Here we report TimeLapse-seq, which uses …
information about the sequenced RNA. Here we report TimeLapse-seq, which uses …
Single-cell RNA sequencing analysis: a step-by-step overview
Thanks to innovative sample-preparation and sequencing technologies, gene expression in
individual cells can now be measured for thousands of cells in a single experiment. Since its …
individual cells can now be measured for thousands of cells in a single experiment. Since its …