The distribution of immunocompetent cells in the genital tract of HIV-positive women

A Olaitan, MA Johnson, A MacLean, LW Poulter - Aids, 1996 - journals.lww.com
Objective: To study the distribution of immunocompetent cells in the female lower genital
tract and to determine whether it is altered in HIV infection. Methods: Colposcopically …

Immunity in the female lower genital tract and the impact of HIV infection

SM Ahmed, H Al‐Doujaily, MA Johnson… - Scandinavian …, 2001 - Wiley Online Library
This study investigates the distribution of immunocompetent cells in the ectocervix, and
cytokine and immunoglobulin (Ig) levels in cervicovaginal secretions to determine whether …

T-lymphocyte profile and total and virus-specific immunoglobulin concentrations in the cervix of HIV-1-infected women

AJ Quayle, AP Kourtis, S Cu-Uvin… - JAIDS Journal of …, 2007 - journals.lww.com
Background: The mucosal lymphocyte population is the largest in the body, and the
gastrointestinal compartment has been well characterized in HIV infection. Much less is …

Impact of human immunodeficiency virus 1 infection and inflammation on the composition and yield of cervical mononuclear cells in the female genital tract

NN Nkwanyana, PP Gumbi, L Roberts, L Denny… - …, 2009 - Wiley Online Library
Cervical cytobrush sampling is a relatively non‐invasive method for obtaining mucosal cells
from the female genital tract. To define mucosal immune cells sampled by cervical …

CD4 T‐cell count, viral load, and squamous intraepithelial lesions in women infected with the human immunodeficiency virus

M Cardillo, R Hagan, J Abadi… - Cancer …, 2001 - Wiley Online Library
BACKGROUND Recent studies have reported an increased incidence of squamous
intraepithelial lesions in women infected with the human immunodeficiency virus (HIV) …

Distribution of immune cells in the human cervix and implications for HIV transmission

RT Trifonova, J Lieberman… - American journal of …, 2014 - Wiley Online Library
Problem Knowledge of the mucosal immune cell composition of the human female genital
tract is important for understanding susceptibility to HIV‐1. Method of study We developed …

Changes to the cytokine microenvironment in the genital tract mucosa of HIV+ women

Olaitan, Reid, Poulter - Clinical & Experimental Immunology, 1998 - Wiley Online Library
As previous studies have indicated that genital tract mucosal T cell function may be impaired
in HIV infection, we investigated the T cell cytokine mRNA in the genital tract mucosa of HIV …

Stable CD4 expression and local immune activation in the ectocervical mucosa of HIV-infected women

T Hirbod, J Kimani, A Tjernlund, J Cheruiyot… - The Journal of …, 2013 - journals.aai.org
Studies using genital tissue samples from HIV-infected women might provide important
information about HIV susceptibility and transmission. In this study, ectocervical biopsies …

Lymphocyte shedding from genital tract of human immunodeficiency virus–infected women: immunophenotypic and clinical correlates

AD Bardeguez, JH Skurnick, G Perez, JM Colon… - American journal of …, 1997 - Elsevier
OBJECTIVE: Our purpose was to describe the lymphocyte subpopulations in genital tract
samples from human immunodeficiency virus–infected women and the clinical correlates …

Evaluation of immunologic markers in cervicovaginal fluid of HIV-infected and uninfected women: implications for the immunologic response to HIV in the female …

ES Beverly, RD D'Amico, AL Landay… - JAIDS Journal of …, 1997 - journals.lww.com
We analyzed 21 cervicovaginal lavage (CVL) specimens from 19 women participating in the
Women's Interagency HIV Study to characterize levels of antibody, cytokine, and …