Thyrotropin suppressive therapy in thyroid carcinoma: what are the targets?

G Brabant - The Journal of Clinical Endocrinology & Metabolism, 2008 - academic.oup.com
Published guidelines on the treatment of thyroid carcinoma support TSH suppressive
therapy as the standard of care for long-term follow-up after initial surgery and sequential …

Thyrotropin suppression and disease progression in patients with differentiated thyroid cancer: results from the National Thyroid Cancer Treatment Cooperative …

DS Cooper, B Specker, M Ho, M Sperling… - Thyroid, 1998 - liebertpub.com
The ideal therapy for differentiated thyroid cancer is uncertain. Although thyroid hormone
treatment is pivotal, the degree of thyrotropin (TSH) suppression that is required to prevent …

Thyroid hormone therapy in differentiated thyroid cancer

G Grani, V Ramundo, A Verrienti, M Sponziello… - Endocrine, 2019 - Springer
Surgery—with or without postoperative radioiodine—is the standard of care for most patients
with differentiated thyroid carcinoma (DTC). Thyroid hormone replacement therapy is the …

Does postoperative thyrotropin suppression therapy truly decrease recurrence in papillary thyroid carcinoma? A randomized controlled trial

I Sugitani, Y Fujimoto - The Journal of Clinical Endocrinology & …, 2010 - academic.oup.com
Context: TSH suppression therapy has been used to decrease thyroid cancer recurrence.
However, validation of effects through studies providing a high level of evidence has been …

The effect of thyrotropin suppression on survival outcomes in patients with differentiated thyroid cancer: A systematic review and meta-analysis

S Gubbi, M Al-Jundi, P Foerster, S Cardenas, G Butera… - Thyroid, 2024 - liebertpub.com
Background: Long-term management of intermediate-and high-risk differentiated thyroid
cancer (DTC) involves thyrotropin (TSH) suppression with thyroid hormone to prevent …

TSH suppressive therapy: an overview of long-term clinical consequences

DS Cooper - Hormones, 2010 - Springer
An overview of long-term clinical consequences of TSH suppressive therapy provides
evidence that serum TSH levels should be maintained at levels< 0.1 mU/l in high-risk (stage …

Thyroid stimulating hormone suppression in the long-term follow-up of differentiated thyroid cancer

B Freudenthal, GR Williams - Clinical Oncology, 2017 - Elsevier
Differentiated thyroid cancer is the most common form of thyroid cancer and its prognosis is
favourable in most cases. Suppression of thyroid stimulating hormone (TSH) by supra …

Benefits of thyrotropin suppression versus the risks of adverse effects in differentiated thyroid cancer

B Biondi, DS Cooper - Thyroid, 2010 - liebertpub.com
Background: Despite clinical practice guidelines for the management of differentiated thyroid
cancer (DTC), there are no recommendations on the optimal serum thyrotropin (TSH) …

Thyroid hormone suppression therapy

B Biondi, DS Cooper - Endocrinology and Metabolism Clinics, 2019 - endo.theclinics.com
The rationale behind thyroid hormone suppression therapy is the knowledge that thyroid-
stimulating hormone (TSH), secreted by the pituitary, affects growth and proliferation of …

Thyrotropin suppression for papillary thyroid cancer: a physician survey study

M Papaleontiou, DW Chen, M Banerjee… - Thyroid, 2021 - liebertpub.com
Background: Current guidelines recommend against thyrotropin (TSH) suppression in low-
risk differentiated thyroid cancer patients; however, physician practices remain …