[HTML][HTML] Compulsive methamphetamine taking in the presence of punishment is associated with increased oxytocin expression in the nucleus accumbens of rats

IN Krasnova, MC Gerra, D Walther, S Jayanthi… - Scientific reports, 2017 - nature.com
Methamphetamine addiction is mimicked in rats that self-administer the drug. However,
these self-administration (SA) models do not include adverse consequences that are …

[HTML][HTML] Increased expression of proenkephalin and prodynorphin mRNAs in the nucleus accumbens of compulsive methamphetamine taking rats

JL Cadet, IN Krasnova, D Walther, C Brannock… - Scientific reports, 2016 - nature.com
Addiction is associated with neuroadaptive changes in the brain. In the present paper, we
used a model of methamphetamine self-administration during which we used footshocks to …

[HTML][HTML] Incubation of methamphetamine craving in punishment-resistant individuals is associated with activation of specific gene networks in the rat dorsal striatum

AP Daiwile, MT McCoy, B Ladenheim… - Molecular …, 2024 - nature.com
Methamphetamine use disorder (MUD) is characterized by loss of control over compulsive
drug use. Here, we used a self-administration (SA) model to investigate transcriptional …

Oxytocin in the nucleus accumbens core reduces reinstatement of methamphetamine‐seeking behaviour in rats

SJ Baracz, NA Everett, IS McGregor… - Addiction …, 2016 - Wiley Online Library
The psychostimulant methamphetamine (METH) is an addictive illicit drug. Systemic
administration of the neuropeptide oxytocin modulates METH‐related reward and METH …

Chronic methamphetamine self‐administration dysregulates oxytocin plasma levels and oxytocin receptor fibre density in the nucleus accumbens core and …

SJ Baracz, LM Parker, AS Suraev… - Journal of …, 2016 - Wiley Online Library
The neuropeptide oxytocin attenuates reward and abuse for the psychostimulant
methamphetamine (METH). Recent findings have implicated the nucleus accumbens (NA c) …

Methamphetamine abstinence induces changes in μ-opioid receptor, oxytocin and CRF systems: Association with an anxiogenic phenotype

P Georgiou, P Zanos, JA Garcia-Carmona, S Hourani… - …, 2016 - Elsevier
The major challenge in treating methamphetamine addicts is the maintenance of a drug free-
state since they experience negative emotional symptoms during abstinence, which may …

Regionally specific effects of oxytocin on reinstatement of cocaine seeking in male and female rats

RA Weber, CN Logan, KC Leong, J Peris… - International Journal …, 2018 - academic.oup.com
Background Oxytocin reduces cued reinstatement of cocaine seeking in male and female
rats, but the underlying neurobiology has not been uncovered. The majority of effort on this …

Oxytocin decreases methamphetamine self-administration, methamphetamine hyperactivity, and relapse to methamphetamine-seeking behaviour in rats

DS Carson, JL Cornish, AJ Guastella, GE Hunt… - …, 2010 - Elsevier
There is emerging evidence that the neuropeptide oxytocin may be utilised as a treatment
for various psychopathologies, including drug addictions. Here we used an animal model to …

[HTML][HTML] The involvement of oxytocin in the subthalamic nucleus on relapse to methamphetamine-seeking behaviour

SJ Baracz, NA Everett, JL Cornish - PloS one, 2015 - journals.plos.org
The psychostimulant methamphetamine (METH) is an addictive drug of abuse. The
neuropeptide oxytocin has been shown to modulate METH-related reward and METH …

Compulsive methamphetamine taking under punishment is associated with greater cue-induced drug seeking in rats

OV Torres, S Jayanthi, B Ladenheim, MT McCoy… - Behavioural brain …, 2017 - Elsevier
Methamphetamine (METH) addicts lose control over drug consumption despite suffering
multiple adverse medicolegal consequences. To mimic the negative events associated with …