Systemic sclerosis (SSc) is a systemic, immune-mediated chronic disorder characterized by
small vessel alterations and progressive fibrosis of the skin and internal organs. The …

Systemic sclerosis (SSc) is a complex rheumatologic autoimmune disease in which
inflammation, fibrosis, and vasculopathy share several pathogenic pathways that lead to …

ABSTRACT Introduction: Systemic sclerosis (SSc) is a complex autoimmune connective
tissue disease characterized by chronic and progressive tissue and organ fibrosis with …

Fibrosis of the skin and of internal organs, autoimmunity, and vascular inflammation are
hallmarks of Systemic Sclerosis (SSc). The injury and activation of endothelial cells, with …

Systemic sclerosis (SSc) is a complex disease characterized by early microvascular
abnormalities, immune dysregulation and chronic inflammation, and subsequent fibrosis of …

Systemic sclerosis (SSc) is an autoimmune disorder of unknown etiology characterized by
severe and often progressive cutaneous and visceral fibrosis, pronounced alterations in the …

Systemic sclerosis (SSc) has the highest cause-specific mortality of all the connective tissue
diseases, and the aetiology of this complex and heterogeneous condition remains an …

Systemic sclerosis (SSc) is a systemic autoimmune disease characterized by extensive
fibrotic changes in various organs, including skin and lung. Although the etiology of SSc …

Systemic sclerosis (SSc or scleroderma) is a progressive and highly debilitating
autoimmune disorder characterized by inflammation, vasculopathy, and extensive fibrosis …

Systemic sclerosis is an autoimmune disease characterised by vascular dysfunction,
impaired angiogenesis, inflammation and fibrosis. There is no currently accepted disease …