Cytogenetics in acute leukemia

K Mrozek, NA Heerema, CD Bloomfield - Blood reviews, 2004 - Elsevier
Cytogenetic analyses in acute myeloid leukemia (AML) and acute lymphoblastic leukemia
(ALL) have revealed a great number of non-random chromosome abnormalities. In many …

Cytogenetics in acute myeloid leukemia

C Schoch, T Haferlach - Current oncology reports, 2002 - Springer
Cytogenetic analysis is the most important diagnostic tool for determining prognosis in acute
myeloid leukemia (AML). In the majority of patients with AML, acquired clonal chromosome …

Clinical significance of cytogenetics in acute myeloid leukemia.

K Mrózek, K Heinonen, A de la Chapelle… - Seminars in …, 1997 - europepmc.org
Cytogenetic studies of acute myeloid leukemia (AML) have revealed that the majority of
patients display acquired chromosome aberrations. Numerous recurrent karyotypic …

The clinical significance of cytogenetic abnormalities in acute myeloid leukaemia

D Grimwade - Best practice & research Clinical haematology, 2001 - Elsevier
During the last three decades it has become apparent that the majority of cases of acute
myeloid leukaemia (AML) are characterized by at least one of a variety of recurrent …

Clinical importance of cytogenetics in acute myeloid leukaemia

K Mrózek, K Heinonen, CD Bloomfield - Best Practice & Research Clinical …, 2001 - Elsevier
Acquired chromosome aberrations are present in the marrow of most patients with acute
myeloid leukaemia (AML) at diagnosis. Cytogenetically, AML is a very heterogeneous …

Diagnostic and prognostic value of cytogenetics in acute myeloid leukemia

D Grimwade, K Mrózek - Hematology/Oncology Clinics, 2011 - hemonc.theclinics.com
The last 4 decades have seen major advances in understanding the genetic basis of acute
myeloid leukemia (AML), paralleled by substantial improvements in survival of children and …

Comparison of cytogenetic and molecular cytogenetic detection of chromosome abnormalities in 240 consecutive adult patients with acute myeloid leukemia

S Fröhling, S Skelin, C Liebisch, C Scholl… - Journal of Clinical …, 2002 - ascopubs.org
PURPOSE: To prospectively compare cytogenetic and molecular cytogenetic analysis for
the detection of the most relevant chromosome abnormalities in a large series of patients …

Quantitative acute leukemia cytogenetics

F Mitelman, S Heim - Genes, Chromosomes and Cancer, 1992 - Wiley Online Library
Using literature data on cytogenetic abnormalities in 3,612 cases of acute myeloid leukemia
(AML) and 1,551 cases of acute lymphocytic leukemia (ALL), we have attempted to quantify …

Acute lymphoblastic leukemia

CJ Harrison, B Johansson - … Cytogenetics: Chromosomal and …, 2015 - Wiley Online Library
Acute lymphoblastic leukemia (ALL) is classified as B‐lineage ALL (B‐ALL) and T‐lineage
ALL (T‐ALL). The incidence of ALL is almost three times higher in white than black children …

Cytogenetic, molecular genetic, and clinical characteristics of acute myeloid leukemia with a complex karyotype

K Mrózek - Seminars in oncology, 2008 - Elsevier
Patients with acute myeloid leukemia (AML) harboring three or more acquired chromosome
aberrations in the absence of the prognostically favorable t (8; 21)(q22; q22), inv …