Psoriasis is caused by a complex interplay between the immune system, psoriasis-
associated susceptibility loci, autoantigens, and multiple environmental factors. Over the last …

T helper (Th) cells producing interleukin (IL)-17, IL-22, and tumor necrosis factor (TNF) form
the key T cell population driving psoriasis pathogenesis. They orchestrate the inflammation …

Psoriasis vulgaris is a chronic, debilitating skin disease that affects millions of people
worldwide. There is no mouse model that accurately reproduces all facets of the disease, but …

Psoriasis vulgaris is a common, heterogeneous, chronic inflammatory skin disease
characterized by thickened, red, scaly plaques and systemic inflammation. Psoriasis is also …

Research on psoriasis pathogenesis has largely increased knowledge on skin biology in
general. In the past 15 years, breakthroughs in the understanding of the pathogenesis of …

Psoriasis is a chronic inflammatory skin condition associated with immune dysregulation.
The immunologic cascade mediated by the interleukin (IL)-17 pathway plays a critically …

Psoriasis is a chronic, inflammatory, immune-mediated skin condition that affects 3 to 4% of
the adult US population, characterized by well-demarcated, erythematous plaques with …

Psoriasis vulgaris is a multi-factorial heritable disease characterized by severe inflammation
resulting in poorly differentiated, hyperproliferative keratinocytes. Recent advances in …

Psoriasis and psoriatic arthritis are chronic inflammatory diseases of unknown etiology,
affecting 2–3% of the world population. Initially, psoriasis was thought to be a hyper …

Psoriasis vulgaris, affecting the skin, is one of the most common organ-specific autoimmune
diseases in humans. Until recently, psoriasis was treated by agents or approaches …