Anaerobic metabolism occurs in the substratum of gonococcal biofilms and may be sustained in part by nitric oxide
ML Falsetta, AG McEwan, MP Jennings… - Infection and …, 2010 - Am Soc Microbiol
Neisseria gonorrhoeae is the etiologic agent of gonorrhea, which has been among the most
frequently reported communicable diseases in the United States since 1960. Women …
frequently reported communicable diseases in the United States since 1960. Women …
Transcriptional profiling identifies the metabolic phenotype of gonococcal biofilms
ML Falsetta, TB Bair, SC Ku… - Infection and …, 2009 - Am Soc Microbiol
Neisseria gonorrhoeae, the etiologic agent of gonorrhea, is frequently asymptomatic in
women, often leading to chronic infections. One factor contributing to this may be biofilm …
women, often leading to chronic infections. One factor contributing to this may be biofilm …
The Composition and Metabolic Phenotype of Neisseria gonorrhoeae Biofilms
ML Falsetta, CT Steichen, AG McEwan, C Cho… - Frontiers in …, 2011 - frontiersin.org
Neisseria gonorrhoeae has been shown to form biofilms during cervical infection. Thus,
biofilm formation may play an important role in the infection of women. The ability of N …
biofilm formation may play an important role in the infection of women. The ability of N …
Proteomic Analysis of Neisseria gonorrhoeae Biofilms Shows Shift to Anaerobic Respiration and Changes in Nutrient Transport and Outermembrane Proteins
NJ Phillips, CT Steichen, B Schilling, DMB Post… - PLoS …, 2012 - journals.plos.org
Neisseria gonorrhoeae, the causative agent of gonorrhea, can form biofilms in vitro and in
vivo. In biofilms, the organism is more resistant to antibiotic treatment and can serve as a …
vivo. In biofilms, the organism is more resistant to antibiotic treatment and can serve as a …
Transcriptional responses of Neisseria gonorrhoeae to glucose and lactate: implications for resistance to oxidative damage and biofilm formation
Understanding how bacteria adapt to different environmental conditions is crucial for
advancing knowledge regarding pathogenic mechanisms that operate during infection as …
advancing knowledge regarding pathogenic mechanisms that operate during infection as …
Gonococcal Nitric Oxide Reductase Is Encoded by a Single Gene, norB, Which Is Required for Anaerobic Growth and Is Induced by Nitric Oxide
TC Householder, EM Fozo, JA Cardinale… - Infection and …, 2000 - Am Soc Microbiol
The gene encoding a nitric oxide reductase has been identified in Neisseria gonorrhoeae.
The norB gene product shares significant identity with the nitric oxide reductases in …
The norB gene product shares significant identity with the nitric oxide reductases in …
Deep sequencing-based analysis of the anaerobic stimulon in Neisseria gonorrhoeae
VM Isabella, VL Clark - BMC genomics, 2011 - Springer
Background Maintenance of an anaerobic denitrification system in the obligate human
pathogen, Neisseria gonorrhoeae, suggests that an anaerobic lifestyle may be important …
pathogen, Neisseria gonorrhoeae, suggests that an anaerobic lifestyle may be important …
Neisseria gonorrhoeae blocks epithelial exfoliation by nitric-oxide-mediated metabolic cross talk to promote colonization in mice
P Muenzner, CR Hauck - Cell host & microbe, 2020 - cell.com
Several pathogens suppress exfoliation, a key defense of epithelia against microbial
colonization. Common among these pathogens, exemplified by Neisseria gonorrhoeae, is …
colonization. Common among these pathogens, exemplified by Neisseria gonorrhoeae, is …
Interaction of pathogenic Neisseria with host defenses. What happens in vivo?
RF Rest, J Liu, R Talukdar, JV Frangipane… - Annals of the New …, 1994 - europepmc.org
N. gonorrhoeae initiates infection by adhering to and invading columnar epithelial cells.
Over time these activities often induce inflammation, with the influx of neutrophils and serum …
Over time these activities often induce inflammation, with the influx of neutrophils and serum …
Neisseria gonorrhoeae elicits extracellular traps in primary neutrophil culture while suppressing the oxidative burst
CW Gunderson, HS Seifert - MBio, 2015 - Am Soc Microbiol
Neisseria gonorrhoeae (the gonococcus) causes gonorrhea and is uniquely adapted to
survive within the human reproductive tract. Gonococci evade host immune surveillance in …
survive within the human reproductive tract. Gonococci evade host immune surveillance in …