Platelets contain abundant growth factors and cytokines that have a positive influence on the
migration and proliferation of different cell types by modulating its physiopathological …

Background aims Chronic wounds are a common complication of diabetes. Fibroblast-
myofibroblast differentiation is important for wound repair, which is commonly impaired in …

Increasing evidence shows that some cells from peripheral blood fibroblast-like
mononuclear cells have the capacity to differentiate into mesenchymal lineages. However …

Background: Skin wounds continue to be a global health problem. Several cellular therapy
protocols have been used to improve and accelerate skin wound healing. Here, we …

Platelet gel derived from peripheral blood is widely applied in many clinical fields of surgery
as biomaterial containing growth factors with high proliferative properties. In 2010, we …

Diabetic foot ulcer (DFU) is a main diabetic complication with unmet treatment needs. This
study applied human umbilical cord-derived mesenchymal stem cells-hyaluronic acid …

Background Although mesenchymal stem cells (MSCs) are used as therapeutic agents for
skin injury therapy, few studies have reported the effects of dosing duration and delivery …

Mesenchymal stem cells (MSCs) have been known as a reliable and effective source to
repair damaged tissues. The differentiation and self-renewal ability, easy access, immune …

Background Diabetic wounds remain a challenging clinical problem, which requires further
treatment development. Published data showed that dermis-derived stem/progenitor cells …

Our aim was to study the effect of platelet-rich plasma (PRP) on the proliferation of bone-
marrow-derived mesenchymal stem cells (BM-MSCs) and to investigate their roles in the …