Comparative study of the possible protective effects of cinnamic acid and cinnamaldehyde on cisplatin‐induced nephrotoxicity in rats

ESM El‐Sayed, OM Abd El‐Raouf… - … of Biochemical and …, 2013 - Wiley Online Library
This study aimed to assess the protective effect of cinnamic acid (CA) and cinnamaldehyde
(CD) against cisplatin‐induced nephrotoxicity. A single dose of cisplatin (5 mg/kg), injected …

Carnosic acid attenuates renal injury in an experimental model of rat cisplatin-induced nephrotoxicity

BD Sahu, KKR Rentam, UK Putcha, M Kuncha… - Food and Chemical …, 2011 - Elsevier
Nephrotoxicity is one of the serious dose limiting side effects of cisplatin when used in the
treatment of various malignant conditions. Accumulating evidence suggests that oxidative …

Preventive effect of aminoguanidine compared to vitamin E and C on cisplatin-induced nephrotoxicity in rats

S Atasayar, H Gürer-Orhan, H Orhan, B Gürel… - Experimental and …, 2009 - Elsevier
In this study, the antioxidant effect of aminoguanidine on nephrotoxicity of a single dose of
cisplatin is investigated and compared with the effects of well-known antioxidants vitamin C …

Phenolic acids (gallic and tannic acids) modulate antioxidant status and cisplatin induced nephrotoxicity in rats

SF Akomolafe, AJ Akinyemi… - International scholarly …, 2014 - Wiley Online Library
Cisplatin (cis‐diamminedichloroplatinum (II) or CDDP), used in the treatment of many solid‐
tissue cancers, has its chief side‐effect in nephrotoxicity. Hence, this study sought to …

Cinnamic acid attenuates cisplatin-induced hepatotoxicity and nephrotoxicity

AM Aref, AA Tohamy, AE Abdel Moneim, RH Sayed - 2016 - repository.msa.edu.eg
We investigated the effects of cinnamic acid (CA, 20 mg/kg body weight) on cisplatin (CP)-
induced hepto and nephrotoxicity in mice. CP (5 mg/kg bwt) was injected intraperitoneally …

Thymol and carvacrol prevent cisplatin‐induced nephrotoxicity by abrogation of oxidative stress, inflammation, and apoptosis in rats

ES EM, AA AR, M AM, ELA AA - Journal of biochemical and …, 2015 - Wiley Online Library
The aim of the present study is to assess the possible protective effects of thymol and
carvacrol against cisplatin (CP)‐induced nephrotoxicity. A single dose of CP {6 mg/kg …

Protective effect of carnosine against cisplatin-induced nephrotoxicity in mice

AA Fouad, MA Morsy, W Gomaa - Environmental Toxicology and …, 2008 - Elsevier
The nephroprotective effect of the natural antioxidant carnosine was evaluated in mice with
cisplatin-induced acute renal damage, in which generation of reactive oxygen species plays …

The protective effects of acetylsalicylic acid on free radical production in cisplatin induced nephrotoxicity: an experimental rat model

B Ulubaş, MY Burak Çımen… - Drug and chemical …, 2003 - Taylor & Francis
Cisplatin-induced nephrotoxicity is closely associated with an increase in lipid peroxidation.
In several previous reports it was claimed that acetylsalicylic acid (ASA) shows its …

Renoprotective mechanisms of chlorogenic acid in cisplatin-induced kidney injury

R Domitrović, O Cvijanović, V Šušnić, N Katalinić - Toxicology, 2014 - Elsevier
The aim of this study was to investigate the renoprotective activity of chlorogenic acid (CA) in
a murine model of cisplatin (CP)-induced kidney injury. Male BALB/cN mice were gavaged …

The effect of N-acetylcysteine on inflammation and oxidative stress in cisplatin-induced nephrotoxicity: a rat model

İ Güntürk, C Yazici, SK Köse, F Dağli… - Turkish Journal of …, 2019 - journals.tubitak.gov.tr
Background/Aim: Cisplatin is a highly effective chemotherapeutic agent used in the
treatment of solid organ cancers. Besides its chemotherapeutic effectiveness, cisplatin …