Antibody responses after mRNA-based COVID-19 vaccination in residential older adults: implications for reopening

DA Nace, KE Kip, JW Mellors, OMP Palmer… - Journal of the American …, 2021 - Elsevier
Objective COVID-19 disproportionately impacts residents in long-term care facilities. Our
objective was to quantify the presence and magnitude of antibody response in vaccinated …

Humoral immunity induced by mRNA COVID-19 vaccines in nursing home residents previously infected with SARS-CoV-2

G Fedele, A Palmieri, C Damiano, A Di Lonardo… - Aging Clinical and …, 2022 - Springer
Background Nursing home (NH) residents suffered the greatest impact of the COVID-19
pandemic. Limited data are available on vaccine-induced immunity and on the protection …

Antibody responses to third-dose mRNA vaccines in nursing home and assisted living residents

A Zhang, JA Breznik, R Clare, I Nazy… - Journal of the American …, 2022 - jamda.com
Methods In this serial cross-sectional analysis, we examined SARS-CoV-2 neutralizing
antibody titers after both second and third vaccination in nursing home residents, and after …

Persistence and protective potential of SARS-CoV-2 antibody levels after COVID-19 vaccination in a West Virginia nursing home cohort

K Smoot, J Yang, DH Tacker, S Welch… - JAMA Network …, 2022 - jamanetwork.com
Importance West Virginia prioritized SARS-CoV-2 vaccine delivery to nursing home facilities
because of increased risk of severe illness in elderly populations. However, the persistence …

Reduced magnitude and durability of humoral immune responses to COVID-19 mRNA vaccines among older adults

MA Brockman, F Mwimanzi, HR Lapointe… - The Journal of …, 2022 - academic.oup.com
Background The magnitude and durability of immune responses to coronavirus disease
2019 (COVID-19) mRNA vaccines remain incompletely characterized in the elderly …

Antibody response after COVID-19 mRNA vaccination in relation to age, sex, and side effects

P Naaber, V Jürjenson, A Adamson, E Sepp… - Sex, and Side …, 2021 - papers.ssrn.com
Background: Although the SARS-CoV2 mRNA vaccines have proven high efficacy in clinical
trials, there is limited data on the impact of age, sex, and side effects on vaccine-induced …

Determinants of humoral and cellular immune responses to three doses of mRNA SARS-CoV-2 vaccines in older adults: A longitudinal cohort study

A Ravussin, AH Robertson, AS Wolf, K Blix… - The Lancet Healthy …, 2023 - thelancet.com
Background Older age is associated with poorer outcomes to COVID-19 infection. The
Norwegian Institute of Public Health established a longitudinal cohort of adults aged 65–80 …

Older adults mount less durable humoral responses to two doses of COVID-19 mRNA vaccine but strong initial responses to a third dose

F Mwimanzi, HR Lapointe, PK Cheung… - The Journal of …, 2022 - academic.oup.com
Background Third coronavirus disease 2019 (COVID-19) vaccine doses are broadly
recommended, but immunogenicity data remain limited, particularly in older adults. Methods …

Comparative risks of potential adverse events following COVID-19 mRNA vaccination among older US adults

DA Harris, KN Hayes, AR Zullo, V Mor… - JAMA Network …, 2023 - jamanetwork.com
Importance Head-to-head safety comparisons of the mRNA vaccines for SARS-CoV-2 are
needed for decision making; however, current evidence generalizes poorly to older adults …

Safety and immunogenicity of SARS-CoV-2 mRNA-1273 vaccine in older adults

EJ Anderson, NG Rouphael, AT Widge… - … England Journal of …, 2020 - Mass Medical Soc
Background Testing of vaccine candidates to prevent infection with severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) in an older population is important, since increased …