Archaea, along with Bacteria and Eukarya, are the three domains of life. In all living cells,
chromatin proteins serve a crucial role in maintaining the integrity of the structure and …

Histones wrap DNA to form nucleosome particles that compact eukaryotic genomes. Variant
histones have evolved crucial roles in chromosome segregation, transcriptional regulation …

Compaction of DNA into chromatin is a characteristic feature of eukaryotic organisms. The
core (H2A, H2B, H3, H4) and linker (H1) histone proteins are responsible for this compaction …

Genome remodeling and exchange of sequences are widespread in the prokaryotic world
and mosaic genomes challenge the classification of prokaryotes, which cannot be properly …

For DNA to be used as an informational molecule it must exist in the cell on the edge of
stability because all genomic processes require local controlled melting. This presents …

Psychrophilic archaea are abundant and perform critical roles throughout the Earth's
expansive cold biosphere. Here we report the first complete genome sequence for a …

RNA polymerase must surmount translocation barriers for continued transcription. In
Eukarya and most Archaea, DNA‐bound histone proteins represent the most common and …

Temperature is a key variable in biological processes. However, a complete understanding
of biological temperature adaptation is lacking, in part because of the unique constraints …

KEOPS is an important cellular complex conserved in Eukarya, with some subunits
conserved in Archaea and Bacteria. This complex was recently found to play an essential …

Archaea comprise one of the three distinct domains of life (with bacteria and eukaryotes).
With 16 complete archaeal genomes sequenced to date, comparative genomics has …